Project Grant R21AI194017
Award Date 8/15/25
Completion Date 7/31/27
Dollars Obligated $452K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Texas, USA
Similar Awards
- This $698,349 Project Grant awarded on February 25, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the development of an "Integrated Multiplexed Diagnostic Assay Targeting Fusion Lipoproteins and Cardiolipin for Detection of Treponemal and Nontreponemal Antibodies in Syphilis Patients." The goal is to create a rapid, point-of-care diagnostic test that can definitively diagnose...
- This federal Project Grant award of $283,694 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research by Dalhousie University to investigate how the syphilis bacterium, Treponema pallidum, interacts with the cervicovaginal epithelial barrier and whether the vaginal microbiome influences susceptibility to T. pallidum infection. The research aims to advance the understanding of syphilis transmission dynamics and...
- This Project Grant award of $448,150 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to explore how the syphilis-causing bacterium Treponema pallidum avoids complement-mediated killing by recruiting the human complement inhibitor Factor H. The goal is to improve understanding of syphilis pathogenesis and identify new control strategies, as syphilis remains a public health concern...
- This federal Project Grant award of $445,250.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to establish a mouse model of congenital syphilis (CS) and determine changes in the host immune response. The primary goals are to lay the foundation for developing improved diagnostics and vaccines for syphilis, a sexually transmitted disease with increasing global incidence. The grant, awarded to...
- The University of Connecticut Health Center (UCHC) was awarded a $457,875 Project Grant by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate fundamental aspects of syphilis disease pathogenesis, including nutrient acquisition and environmental sensing by the bacteria Treponema pallidum. The grant, which spans from August 1, 2025 to July 31, 2027, will support research activities to...
- The University of Washington was awarded a $485,375 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant, awarded on August 11, 2025, will fund research to elucidate the role of genetic recombination in Treponema pallidum, the bacterium that causes syphilis. Specifically, the researchers will investigate the mechanisms of homologous recombination in T. pallidum and examine...
- This Project Grant award of $418,360.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Program (CFDA 93.855), aims to systematically analyze Treponema pallidum gene expression under host infection-related conditions. The central hypothesis is that T. pallidum, the bacterium that causes syphilis, alters its gene expression in response to changes in oxygen concentration, temperature, and host interactions, which enables...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $155,686 Project Grant to Baylor College of Medicine under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to optimize Strongyloides testing in an at-risk U.S. population. This project aims to address the public health challenge of strongyloidiasis, a parasitic infection that can cause severe disease in immunosuppressed individuals. The research will focus on improving diagnostic...
- The University of California, Los Angeles (UCLA) was awarded a $627,699 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to conduct a randomized clinical trial to prevent maternal syphilis and congenital syphilis in Rio de Janeiro, Brazil. The project aims to evaluate the use of enhanced serologic screening and point-of-care treponemal testing during prenatal care to address...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $444,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Methodist Hospital Research Institute in Houston, Texas. The grant, titled "Streptococcal Virulence Regulation by a Novel Intercellular Signaling Pathway - Group B Streptococcus (GBS)", aims to characterize a previously unknown intercellular signaling pathway in GBS and determine its contribution to GBS...