This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $881,303 to The Children's Hospital of Philadelphia (CHOP) to conduct high-resolution, whole genome tracking of pathogen transmission and infection in the neonatal intensive care unit (NICU). The key objectives are to use whole genome sequencing and diagnostic allele surveillance to determine bacterial transmission and persistence dynamics within two NICUs, assess the impact of patient case-mix and NICU environmental factors on colonization and infection patterns, and evaluate the efficacy of using near real-time diagnostic allele sequencing to guide targeted infection prevention strategies. The findings are expected to demonstrate the feasibility and effectiveness of this approach in reducing bacterial transmission and invasive infections among vulnerable NICU patients.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $881.3k | 7/17/25 |