Project Grant R01AI185544

Award Date 7/17/25
Completion Date 6/30/30
Dollars Obligated $881K
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Pensilvania, EE. UU.
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The key objectives are to use whole genome sequencing and diagnostic allele surveillance to determine bacterial transmission and persistence dynamics within two NICUs, assess the impact of patient case-mix and NICU environmental factors on colonization and infection patterns, and evaluate the efficacy of using near real-time diagnostic allele sequencing to guide targeted infection prevention strategies. The findings are expected to demonstrate the feasibility and effectiveness of this approach in reducing bacterial transmission and invasive infections among vulnerable NICU patients.

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