Project Grant R01AI193629

Award Date 7/25/25
Completion Date 6/30/29
Dollars Obligated $3.2M
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
This federal Project Grant award, valued at $312,000.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award will support research conducted by the University of Texas Health Science Center at Houston (UTHealth) to develop a single-cell resolution understanding of pathogenesis and antibiotic tolerance in Staphylococcus aureus infections. The research aims to explore the...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $560,178 Project Grant to the University of Wisconsin - Madison. The goal of this 5-year grant, which runs from Jul 25, 2025 to Jun 30, 2030, is to understand the dynamics of the interaction between Staphylococcus aureus bacteriophages, the bacteria, and the mammalian host. Specifically, the research aims to elucidate the...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $267,310 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Illinois in Chicago. The grant, awarded on August 27, 2024, supports research to evaluate the role of a lipoic acid transfer protein in Staphylococcus aureus metabolism and virulence. The project aims to determine how this lipoic acid transfer protein interfaces with other metabolic enzymes to control...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) provides $128,655 to the University of Pittsburgh to enhance surveillance methods for genomic epidemiology in healthcare. The project aims to test the hypothesis that combining real-time whole genome sequencing (WGS) surveillance of bacterial pathogens with targeted environmental cultures will improve identification and control...
This federal Project Grant award of $2,976,652 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to explore polyamine toxicity and resistance in epidemic bacterial skin pathogens, specifically methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes (Group A Streptococcus). The research aims to understand how polyamines enter and kill these bacteria, and how...
This Project Grant award of $2,841,668.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research focused on understanding how the bacterial enzyme SagB in Staphylococcus aureus (S. aureus) modulates the host immune response and promotes infection. The key goals are to determine how SagB-modified peptidoglycan is recognized by immune cells, investigate the mechanism of SagB-dependent IL-1β...
This $3,021,822 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research by Georgetown University to investigate the role of branched-chain fatty acids in the physiology and virulence of Staphylococcus aureus, a leading cause of skin and soft tissue infections. The research aims to: 1) determine the pathway by which S. aureus salvages and synthesizes branched-chain fatty...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $175,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to California State University, Fresno. The grant, titled "Surveillance of Drug-Resistant Bacteria in Resource-Limited Settings: A Focus on Cost-Effective Long-Read Sequencing of Eyedrop-Associated P. Aeruginosa and Locally Sourced Metagenomic Samples," aims to develop a decentralized antimicrobial resistance...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $189,558 to Duke University to identify genomic determinants of antibiotic treatment failure in Staphylococcus aureus bacteremia (SAB). The primary objectives are to: 1) Use a murine in-vivo evolution model to identify bacterial genotypes associated with SAB treatment failure, and 2) Conduct a genome-wide...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a 5-year, $395,496 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of California, San Francisco. The grant supports a study using metagenomic next-generation sequencing (MNGS) to provide novel insights into pathogen transmission and antimicrobial resistance acquisition in neonatal intensive care units (NICUs). The research aims to: 1) identify nosocomial transmission...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to develop real-time detection methods for Staphylococcus aureus transmission in hospital settings. The $3,210,845 award to New York University aims to integrate whole-genome sequencing with weekly colonization sampling to analyze transmission dynamics and create predictive models that can optimize surveillance strategies. The goal is to shift hospitals from reactive to proactive management of S. aureus outbreaks, which can reduce morbidity, mortality, and healthcare costs associated with hospital-acquired infections. The project period runs from July 2025 to June 2029.

Generated 8/5/25, 6:47 AM