Project Grant R01AI184936
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $427,625 Project Grant on February 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct fundamental research on viral infection sensing mechanisms in Caenorhabditis elegans. The research will investigate how the model organism recognizes and responds to RNA virus infection, specifically focusing on Orsay virus (ORV), the...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $596,115 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, with completion targeted for July 31, 2030. This five-year award supports investigator-initiated biomedical research examining the long-term impact of persistent parainfluenza virus infection, specifically focusing on how human...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Washington University a Project Grant totaling $427,626 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 1, 2026, through March 31, 2028. The award funds research to identify host factors that mediate the nuclear retention of unspliced and partially spliced human immunodeficiency virus type 1 (HIV-1) transcripts. The research addresses a...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Washington University a Project Grant of $144,196 effective November 1, 2025, through April 30, 2028, under the Allergy and Infectious Diseases Research program (CFDA 93.855). Principal Investigator Madison A. Stringer will conduct biophysical and biochemical characterization of the phosphoprotein (P) from Borna Disease Virus, specifically focusing on the functional properties of the...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Washington University a Project Grant of $427,625.00 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 15, 2026, with a completion date of May 31, 2028. This research project investigates a broad host-range bacteriophage (STAB3) and its novel glycan receptor to advance phage therapy as an alternative treatment for antibiotic-resistant Acinetobacter baumannii...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $715,894 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 8, 2025, for a five-year research initiative extending through July 31, 2030. This award funds fundamental biomedical research investigating the influence of microbial metabolites on mitosome function in Cryptosporidium parvum, a parasitic pathogen...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $155,454 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2027. This award funds research to identify and characterize molecular mechanisms of Venezuelan Equine Encephalitis Virus (VEEV) entry into host cells and to develop enhanced therapeutic interventions targeting...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Washington University a Project Grant of $179,114 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and validate innovative methodologies for high-throughput identification of bacteriophage-host relationships in complex microbial communities. The research will establish a single-cell ribonucleic acid sequencing (scRNA-seq)-based platform designed to rapidly...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Washington University a $638,220 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2031. The grant funds research into DNA ADP-ribosylation mechanisms in bacterial-phage interactions, specifically investigating how bacterial toxin-antitoxin systems (DARTG systems) function in anti-phage defense. The...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2027. The grant supports research to identify and develop novel anti-biofilm therapeutic agents by exploiting bacteriophage mechanisms that penetrate bacterial biofilm matrices. The research focuses on mining...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded Washington University a $388,750 Project Grant on July 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct basic research on astrovirus pathogenesis. The research focuses on defining the critical functions of the stem-loop II (S2M) motif in the lifecycle of astrovirus VA1, the most common cause of astrovirus encephalitis. Using advanced molecular techniques including SHAPE-MAP analysis and reverse genetics, the research team will elucidate the structural and functional role of the S2M RNA motif in viral replication, capsid protein expression, and translation mechanisms. The work will produce scientific knowledge regarding host-pathogen interactions and viral replication strategies, with findings expected to inform future therapeutic and diagnostic development for astrovirus infections. The research project extends through June 30, 2031, and will be conducted at Washington University's St. Louis, Missouri campus. Deliverables include characterization of the S2M motif's mechanism of action, identification of host proteins that interact with the viral RNA structure, and publication of findings in peer-reviewed scientific literature. This award reflects NIAID's continued investment in basic infectious disease research addressing significant human health impacts, including fatal cases of astrovirus-induced encephalitis.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $388.8k | 7/6/26 |