Project Grant R01AI195977
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2027. The grant supports research to identify and develop novel anti-biofilm therapeutic agents by exploiting bacteriophage mechanisms that penetrate bacterial biofilm matrices. The research focuses on mining...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $664,076 under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning April 1, 2026, and concluding March 31, 2031. This research award funds investigator-initiated biomedical research to elucidate the molecular mechanisms by which Staphylococcus aureus alpha-toxin (HLA) impairs antigen-specific T cell responses and...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 4, 2026, with an ultimate completion date of January 31, 2028. This award funds mechanistic research investigating the role of calcineurin, a phosphatase enzyme, in regulating autophagy and protecting the transcription factor TCF-1 in cytotoxic CD8+ T...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $715,894 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 8, 2025, for a five-year research initiative extending through July 31, 2030. This award funds fundamental biomedical research investigating the influence of microbial metabolites on mitosome function in Cryptosporidium parvum, a parasitic pathogen...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2030. This award funds research titled "Advancing Lymphatic Filariasis Elimination with Parasite Genomic Epidemiology," which will deliver comprehensive genomic analysis and characterization of Wuchereria bancrofti...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $773,053 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 6, 2025, with a completion date of May 31, 2030. This research project focuses on elucidating the biosynthesis of beta-1,6-glucan in the cell wall of Cryptococcus neoformans, a fungal pathogen responsible for approximately 150,000 deaths annually,...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 2, 2026, with a completion date of January 31, 2028. The award supports investigator-initiated biomedical research examining viral infection sensing mechanisms in Caenorhabditis elegans (C. elegans), a model organism system. The research will...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $151,040 to The Washington University (Office of Sponsored Research Services) on December 23, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research will be conducted through June 30, 2028, at the university's location in Missouri. This award supports investigator-initiated biomedical research addressing infectious disease...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $233,250 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. This award funds research to optimize culturomic and metagenomic methods for detecting multi-strain Clostridioides difficile (CD) colonization and infection. The project addresses a critical gap in current...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $633,218 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective July 17, 2025, with a completion date of June 30, 2030. This research grant funds a comprehensive investigation into Plasmodium falciparum Niemann-Pick C1-Related Protein 1 (PfNCR1), a cholesterol transporter located at the interface between the...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $638,220 Project Grant effective April 1, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated biomedical research examining DNA ADP-ribosylation mechanisms in bacterial-phage interactions. The research focuses on understanding how bacteria utilize DNA-targeting ADP-ribosyltransferase (DART) toxins as anti-phage defense systems and how co-evolving phages have developed counter-mechanisms through DNA-targeting ADP-ribosylglycobydrolase (ARG) proteins to circumvent these bacterial defenses. The project aims to elucidate fundamental biological functions of these widespread enzyme families and their roles in the ongoing molecular conflict between bacterial and phage systems. The research will be conducted at Washington University's Office of Sponsored Research Services in St. Louis, Missouri, and is expected to generate scientific knowledge, methodological advances, and improved understanding of host-pathogen molecular interactions relevant to infectious disease mechanisms. This award represents the institution's capacity to execute complex fundamental research in immunology and infectious disease biology through the NIH's competitive peer-review process for investigator-initiated grants supporting biomedical research addressing infectious diseases and related biological conflicts.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $638.2k | 4/1/26 |