Project Grant R01AI184571

Award Date 8/6/24
Completion Date 6/30/29
Dollars Obligated $633K
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
New York, NY 10065, USA
Similar Awards
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $404,479 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Rector & Visitors of the University of Virginia, doing business as the University of Virginia. The grant will fund research to (1) identify key Fc receptors and mechanisms mediating antibody transfer across the placental cellular layers, (2) determine antibody Fc features that optimize this transfer, and (3) develop...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to investigate the interplay between maternal antibodies and newborn vaccine responses to influenza virus infection. The $793,102 award, provided from Apr 17, 2025 to Mar 31, 2030, will leverage a non-human primate model to evaluate influenza vaccine responses in infants born to immune and naive mothers. The goal is to...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded a $693,465 Project Grant to Cornell University to conduct research on mapping infant and adult T cell immunity. The project aims to construct a molecular atlas of T cell development in lymph nodes and determine how cellular interactions and communication networks change during CD8+ T cell priming throughout childhood. The research will investigate...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Research Institute at Nationwide Children's Hospital (RINCH) in the amount of $873,600. The grant, titled "INTERROGATING INFANT IMMUNE RESPONSES FOR DIAGNOSIS OF CONGENITAL SYPHILIS INFECTION", aims to investigate the immune responses of infants with congenital syphilis infection. The project will use advanced...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $859,597 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to New York University (NYU) School of Medicine. The grant, awarded on August 2, 2024, supports research to develop a vaccine that can elicit broadly neutralizing antibodies against the HIV-1 fusion peptide epitope. The research aims to build upon previous promising results showing that a recombinant fusion immunogen combining...
This federal Project Grant award, valued at $205,999.00 and effective from December 4, 2024 to November 30, 2029, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports the development of a cohort of young investigators skilled in conducting high-quality translational research in the field of perinatal infectious diseases. Key objectives include encouraging passion for...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $586,250 Project Grant (CFDA 93.855 Allergy and Infectious Diseases Research) to the University of Massachusetts Medical School (UMass Medical) to investigate how distinct age-associated B cell subsets can protect the aged from influenza. The research aims to determine the potential of different age-associated B cell subsets to respond to influenza infection, generate antibody-secreting cells, form B cell memory, and...
This $3,899,298 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research at Rockefeller University to investigate the evolutionary dynamics of antibody development within germinal centers. The award will fund a comprehensive research approach, including the creation of a mouse monoclonal antibody model, deep mutational scans to measure affinity effects of mutations, and...
This federal Project Grant award of $219,456 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will support research to understand how sterile inflammation at the maternal-fetal interface impacts the developing fetal immune system in a non-human primate model. The key objectives are to 1) test the hypothesis that injection of the clotting agent Tisseel into the maternal-fetal interface leads to placental inflammation, and 2)...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $2,601,319.00 to Emory University over a period of 5 years, from June 2024 to April 2029. The funding supports research to understand the epigenetic and transcriptional mechanisms that regulate B cell differentiation and fate decisions, which are critical for humoral immunity and the development of effective vaccines...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $633,074 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Sloan-Kettering Institute for Cancer Research in New York, NY. The grant, awarded on August 6, 2024, will fund a 5-year research project to study maternal B cell and antibody responses during pregnancy. The key objectives are to define the mechanisms that suppress B cell activation to placental antigens, characterize the protective nature of anti-placental antibodies, and evaluate maternal B cell and follicular helper T cell dynamics in response to foreign antigens. This research aims to illuminate how dysregulated B cell and antibody responses contribute to pregnancy complications and inform the design of vaccines to protect mothers and children from infection.

Generated 6/10/25, 4:56 AM