This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to investigate the protective functions of the cytokine interleukin-27 (IL-27) at the maternal-fetal interface during congenital infections. The $556,002 award will fund a 5-year research project to define the immune regulatory and antiviral mechanisms by which IL-27 signaling protects against...
This federal Project Grant award, valued at $205,999.00 and effective from December 4, 2024 to November 30, 2029, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports the development of a cohort of young investigators skilled in conducting high-quality translational research in the field of perinatal infectious diseases. Key objectives include encouraging passion for...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), with CFDA Number 93.855 - Allergy and Infectious Diseases Research, provides up to $589,921 in funding to The Regents of the University of California, San Francisco (UCSF) to support research on how the fetus and placenta avoid rejection by the maternal immune system. The key objectives of this 5-year project include: 1) evaluating the role of glycan-specific IgM natural antibodies in...
This $3,305,720 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant will fund research to define the impact of maternal viral infections and inflammation on immune programming within the fetal brain and lymphoid organs in a non-human primate (NHP) model. The key objectives are to: 1) Use an ex vivo microculture model to determine innate immune pathways activated by...
This $545,686 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to elucidate the mechanisms by which the cytokine interleukin-9 (IL-9) at the maternal-fetal interface promotes preterm labor and birth, and to define the impact of maternal IL-9 on fetal/neonatal outcomes. The primary goals are to: 1) determine how IL-9 signaling in hematopoietic and non-hematopoietic cells at the...
This federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,240,728 to the University of Pittsburgh to investigate the role of innate allorecognition receptors on maternal myeloid cells in regulating the maternal-fetal immune response during pregnancy. The research aims to understand how activating and inhibitory allorecognition receptors on maternal immune...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to investigate the interplay between maternal antibodies and newborn vaccine responses to influenza virus infection. The $793,102 award, provided from Apr 17, 2025 to Mar 31, 2030, will leverage a non-human primate model to evaluate influenza vaccine responses in infants born to immune and naive mothers. The goal is to...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $633,074 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Sloan-Kettering Institute for Cancer Research in New York, NY. The grant, awarded on August 6, 2024, will fund a 5-year research project to study maternal B cell and antibody responses during pregnancy. The key objectives are to define the mechanisms that suppress B cell activation to placental antigens, characterize...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $404,479 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Rector & Visitors of the University of Virginia, doing business as the University of Virginia. The grant will fund research to (1) identify key Fc receptors and mechanisms mediating antibody transfer across the placental cellular layers, (2) determine antibody Fc features that optimize this transfer, and (3) develop...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $430,604 to Imperial College of Science, Technology and Medicine in the United Kingdom to conduct research on the role of placental macrophages in cytomegalovirus (CMV) infection at the maternal-fetal interface. The key objectives are to: 1) investigate the temporal response of placental macrophages (Hofbauer...