Project Grant R01AI182167
- The University of South Florida (USF) received a $480,522 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant supports research to investigate the regulation and role of the secreted proteases of the bacterium Staphylococcus aureus, a major cause of infectious disease. The research aims to elucidate how these enzymes mediate S. aureus pathogenesis and virulence, with...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $401,191 Project Grant to The Johns Hopkins University on June 11, 2025 under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The project aims to characterize the neonatal nasal microbiome following a parent-to-child nasal microbiota transplant, with the goal of developing interventions to prevent life-threatening Staphylococcus aureus infections in neonates. The research focuses on...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $212,169 Project Grant under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to The Johns Hopkins University to advance mentorship at the Johns Hopkins Integrated Center for Combating Antimicrobial Resistant Bacteria. The project summary indicates the principal investigator has conducted pivotal research on antimicrobial resistant infections, leading to clinical guidelines, and has...
- This federal Project Grant award of $208,332 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to advance understanding of how Staphylococcus aureus, a leading global pathogen, causes spine infections in humans. The award to New York University School of Medicine will support research to evaluate the contributions of specific S. aureus virulence factors in enabling the pathogen to evade the human immune system and cause...
- This $226,253 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how the host protein ADAM10 modulates the interactions between neutrophils and the endothelium during Staphylococcus aureus infection. The project aims to generate a spatiotemporal analysis of these key cellular and molecular interactions in the early stages of infection, leveraging...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $769,390 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, to research using ultrasound and microbubbles to augment antibiotic efficacy against periprosthetic joint infections. The project aims to sensitize bacterial aggregates to antibiotics through a combination of antibiotics and ultrasound-triggered...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $638,953 Project Grant to Abvacc, Inc., a biotechnology company in Rockville, Maryland. The grant, running from August 2025 to July 2030, supports the development of an immunotherapeutic antibody cocktail for the treatment of Staphylococcus aureus bacteremia (SAB). The project aims to target multiple mechanisms of growth and immune...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $3,021,822 Project Grant to Georgetown University. The grant supports research to investigate the role of branched-chain fatty acids in the physiology and virulence of Staphylococcus aureus, a leading cause of skin and soft tissue infections, particularly in chronic wound infections where S. aureus often co-occurs with other...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $2,922,220 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University. The grant supports research to advance apoptosis-inducing agents as host-directed therapy for tuberculosis (TB). The research aims to boost host immune responses via the intrinsic apoptosis pathway to reduce Mycobacterium tuberculosis (MTB) growth and enhance the bactericidal activity of...
- This Project Grant award was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $188,916 award supports research by Brigham & Women's Hospital Inc. to investigate how the bacterium Staphylococcus aureus, a leading infectious cause of death globally, is able to evade the immune system and persist during bloodstream infections. The research aims to determine how noncytotoxic (non-toxic)...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3,121,542 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to The Johns Hopkins University. The purpose of this 4-year project, starting on August 1, 2025, is to develop and utilize animal models and novel positron emission tomography (PET) imaging techniques to study Staphylococcus aureus (S. aureus) orthopedic implant-associated infections. This research aims to improve understanding of the pathological features of these infections and evaluate new antibiotic treatment regimens, with a goal of addressing the significant healthcare burden posed by these difficult-to-treat infections. The grant leverages the university's expertise in infectious disease research and advanced PET imaging capabilities to advance medical knowledge and develop new solutions for this clinical challenge.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.1m | 9/12/25 |