This federal Project Grant award totaling $810,312.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will fund research to investigate environmental reservoirs and transmission dynamics of multi-drug resistant Enterobacterales (MDR ENT) in the Chicago area. The key objectives are to: 1) Profile MDR ENT and mobile antibiotic resistance genes in Greater Chicago waterways to identify environmental reservoirs associated with community acquisition of MDR ENT; and 2) Assess risk factors for colonization and transmission of community-acquired MDR ENT among residents in high-risk regions. This will involve extensive environmental sampling, household surveys, and comprehensive genomic characterization of MDR ENT across environmental, animal, and human sources. The findings are expected to inform targeted interventions to reduce community exposure and transmission of these concerning antibiotic-resistant pathogens. The project involves sub-awards to the Rush University Medical Center, University of Chicago, and Virginia Polytechnic Institute & State University to contribute specialized expertise in epidemiology, environmental microbiology, and genomic analysis. This collaborative research aims to address critical gaps in understanding the community-level spread of MDR ENT.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $810.3k | 7/17/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
A1031544S | Rush University Medical Center | Project Grant R01AI179686 | $81.1k | 11/22/24 | |
A1031536S | University Of Chicago | Project Grant R01AI179686 | $12.6k | 11/11/24 | |
A1031511S | Virginia Polytechnic Institute & State University | Project Grant R01AI179686 | $106.5k | 9/5/24 |