Project Grant R21AI185529

Award Date 8/15/24
Completion Date 7/31/26
Dollars Obligated $243K
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Chicago, IL 60612, USA
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This $195,480 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the development and pilot implementation of a low-cost, point-of-care diagnostic assay to detect Neisseria gonorrhoeae infection and molecular markers of antimicrobial resistance in resource-limited settings. The award recipient, Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $229,411 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to Northwestern University to investigate Neisseria gonorrhoeae double-stranded bacteriophage. The research aims to determine whether one or more phage islands can produce phage, explore the regulation of two essential LexA orthologs, and assess whether these phage(s) can infect Neisseria strains or species. This project builds upon the...
This $453,900 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant is funding research to develop a genome editing platform using broadly functioning phage recombinases, which can be used to genetically manipulate a wide range of bacterial species, including clinically relevant pathogens. The goal is to enable direct investigation of the genetic elements driving bacterial...
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This federal Project Grant award, valued at $243,361.00 and running from August 15, 2024 to July 31, 2026, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant is funding a project by Rush University Medical Center in Chicago, Illinois to establish workflows for rapid and inexpensive whole genome sequencing (WGS) of Neisseria gonorrhoeae (NG) directly from urine, throat, and rectal clinical specimens. The goal is to enhance detection of emerging strains of NG with reduced antimicrobial susceptibility, which is a critical public health challenge. The project aims to evaluate this non-culture based molecular surveillance approach to improve monitoring of drug-resistant NG across diverse populations, including those often excluded from traditional culture-based surveillance. The findings are expected to inform strategies for enhanced NG surveillance and increase the timeliness of detecting emerging variants of concern.

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