Project Grant R01AG099094
- Federal Grant Award Summary Cedars-Sinai Medical Center received a $419,321 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded on September 15, 2025, with a completion date of August 31, 2027. This proof-of-concept study will investigate neurocognitive dysfunction in patients with adrenal cortisol insufficiency (ACI), a rare metabolic disease that impairs cognitive function despite standard hydrocortisone treatment. The research will...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded UCLA a $409,687 Project Grant (CFDA 93.113, Environmental Health program) on June 24, 2025, with completion targeted for June 13, 2027. This research initiative delivers a comprehensive epidemiological investigation examining the impacts of wildfire smoke and heat exposure on cognitive decline, mood disorders, and metabolic changes in older adults with Parkinson's Disease (PD)....
- Federal Project Grant Award Summary Cedars-Sinai Medical Center received a $717,957 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective March 1, 2026, through February 28, 2031. This five-year research initiative investigates estrogen signaling mechanisms in urinary tract infection (UTI)-related delirium, with focus on postmenopausal women disproportionately affected by this condition. The research deliverables include...
- Federal Project Grant Award Summary Cedars-Sinai Medical Center received a $3.48M Project Grant from the National Institute of Environmental Health Sciences under the Medical Library Assistance program (CFDA 93.879) for research on artificial intelligence methods applied to large-scale epidemiological studies examining patient medication adherence and tolerability. The award, effective September 15, 2025, through August 31, 2029, builds upon ten years of prior National Library of Medicine-funded...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $5.16 million Project Grant to the University of California, Davis for research under the Aging Research program (CFDA 93.866), effective September 1, 2025 through August 31, 2029. This research initiative examines the relationship between environmental exposures and brain health, particularly as they relate to Alzheimer's disease and related dementias (ADRD). The project will deliver empirical research...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $124,875 Project Grant to Cedars-Sinai Medical Center, effective September 4, 2025, through May 31, 2030, under the Aging Research program (CFDA 93.866). This career development award supports research investigating the role of senescent cells in the heightened susceptibility of elderly and chronically ill patients to infectious diseases. The project, led by Dr. Larissa Langhi Prata, an Assistant Professor of...
- Federal Grant Award Summary Cedars-Sinai Medical Center received a $511,396 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 1, 2025, through July 31, 2030. The award supports basic neuroscience research investigating the diversity of presynaptic function across different neuronal populations, specifically examining how...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Columbia University's Health Sciences Division a $529,744 Project Grant effective February 15, 2026, through January 31, 2031, under the Aging Research program (CFDA 93.866). The award funds research investigating the mechanisms driving Alzheimer's disease progression through the entorhinal cortex-hippocampal circuit. The primary deliverables include longitudinal scientific investigations utilizing two-photon in...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $3.26 million Project Grant to the University of Maryland, Baltimore on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate olfactory dysfunction as a predictor of fine particulate matter (PM2.5) exposure progression to dementia. The research will be conducted over a 47-month period (September 2025 through August 2029) and will deliver comprehensive scientific research aimed at...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $795,848 Project Grant to the University of California, Davis on June 18, 2025, under the Environmental Health program (CFDA 93.113) to conduct research on molecular and neurodevelopmental alterations associated with prenatal wildfire smoke exposures. The research will investigate mechanisms linking prenatal particulate matter (PM2.5) exposures from wildfires to adverse pregnancy and child...
Cedars-Sinai Medical Center received a $701,073 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) on February 15, 2026, with completion scheduled for December 31, 2030. The grant funds a time-sensitive prospective cohort study examining the neurological health effects of wildfire exposure among individuals affected by the January 2025 Los Angeles wildfires. The research will track newly appearing or elevated blood levels of combustion byproducts, biomarkers of neuroinflammation and neuropathology, and serial assessments of neurocognitive function and neurodegeneration in highly exposed populations. The primary deliverables include longitudinal clinical data and scientific evidence documenting the relationship between wildfire-related chemical exposures—including volatile organic compounds such as benzene and semi-volatile organic compounds including perfluorochemicals—and accelerated brain aging or dementia risk markers. The study aims to elucidate mechanistic triggers of wildfire-related neuropathology and generate evidence-based insights into the long-term neurocognitive health impacts of disaster-related environmental exposures. Research will be conducted at Cedars-Sinai's location in West Hollywood, California, positioned to capture and analyze health outcomes in the affected Los Angeles wildland-urban interface population.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $701.1k | 2/10/26 |