This Project Grant award, with a total funding amount of $409,687.00 and an award date of June 24, 2025, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program. The grant aims to assess the impact of wildfire smoke and heat on cognition, mood, and the human metabolome in a vulnerable older population, specifically those with Parkinson's disease (PD). The research will leverage a large case-control study of approximately 1,000 PD patients and 1,000 community controls, analyzing comprehensive data on cognitive status, depressive symptoms, and residential histories. Advanced modeling techniques and metabolomic analysis will be used to explore the biological pathways underlying the effects of wildfire smoke and heat exposure on cognitive decline and mental health in this population. The findings have the potential to shed light on metabolomic features and pathways that influence susceptibility or resilience to these environmental factors in older adults.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $409.7k | 6/23/25 |