Project Grant R21AG091290
- This Project Grant award from the National Institute of Environmental Health Sciences (CFDA 93.879 - Medical Library Assistance) is providing $3,484,662.00 to Cedars-Sinai Medical Center to conduct research on using artificial intelligence (AI) methods for large-scale epidemiological studies. The research will focus on leveraging patient reports of medication adherence and tolerability to gain novel insights into intentional medication non-adherence, which is a significant public health...
- This $2,591,620 Project Grant was awarded by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) to Cedars-Sinai Medical Center in California. The grant is designed to determine the role of hypothalamic neurons in the progression of physiological decline with age, with a focus on understanding the cellular mechanisms responsible for increased frailty in older adults. Key objectives include elucidating the role of arginine-vasopressin (AVP) neurons...
- The National Institute on Aging (NIA) awarded a 3-year, $2,561,480 Project Grant (CFDA 93.866) to Brigham & Women's Hospital to study the post-acute sequelae of SARS-CoV-2 infection (PASC) and subsequent disease progression in individuals with mild cognitive impairment (MCI) or Alzheimer's disease (AD) and related dementias (ADRD). The project aims to: 1) understand the epidemiology of PASC in cognitively impaired individuals; 2) examine the impacts of COVID-19 and PASC on disease...
- This federal Project Grant award in the amount of $124,875.00 was provided by the National Institute on Aging (CFDA 93.866 Aging Research) to Cedars-Sinai Medical Center. The grant supports research by Dr. Larissa Langhi Prata, an Assistant Professor at the Kogod Center on Aging at Mayo Clinic, to investigate the role of senescent cells in the susceptibility of elderly and chronically ill patients to infectious diseases. The research aims to provide insights into the biology of aging and its...
- This Project Grant award of $1,526,628.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research by Cedars-Sinai Medical Center to develop Artificial Intelligence (AI) methods for analyzing echocardiography data to predict biological cardiovascular age and identify trajectories of accelerated versus delayed cardiovascular aging. The research aims to capture an aggregate measure of cardiac aging and identify potential interventions to...
- The Icahn School of Medicine at Mount Sinai received a $3,548,990 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to investigate the influence of stress on the expression of neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) mouse models. The goal is to test the hypothesis that promoting stress resilience could prevent or delay the emergence of AD-associated NPS. The 4-year project, starting on Sep 1, 2025, will examine how stress susceptibility...
- The National Institute on Aging (NIA) awarded a $1,466,297 Project Grant under the Aging Research federal grant program (CFDA 93.866) to the Cedars-Sinai Medical Center, in collaboration with the University of California Los Angeles (UCLA) and the University of Southern California (USC), to establish the Los Angeles Claude D. Pepper Older Americans Independence Center (LA OAIC). This 5-year grant, effective September 1, 2025, aims to extend human healthspan by accelerating and expanding...
- This $2,356,117 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to improve the perioperative management of patients with Alzheimer's disease and related dementias. The primary objectives are to: (1) identify the extent to which surgical patients with these conditions are at increased risk for adverse postoperative outcomes, and (2) estimate the association between various perioperative interventions and the incidence...
- This Project Grant award of $1,631,690.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Beth Israel Deaconess Medical Center, Inc. (Bidmc) supports a research project titled "Proteomic Signatures of Delirium and Long-Term Cognitive Decline in Older Cardiac Surgical Patients." The project aims to use state-of-the-art proteomics analysis to derive and validate a delirium protein signature for cardiac surgery patients, leveraging plasma samples from an ongoing...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the University of Southern California provides $622,401 over 5 years starting January 1, 2025 to research causal models of brain biomarker changes leading to Alzheimer's disease and related dementias (ADRD). The project aims to: 1) fit novel deep learning models to predict ADRD pathology from diffusion MRI data, 2) generate individualized brain morphology prediction maps as "digital...
The Cedars-Sinai Medical Center was awarded a $419,321 Project Grant from the National Institute on Aging (CFDA 93.866 - Aging Research) to conduct a short-term, proof-of-concept study on neurocognitive function profiles in patients with primary and secondary adrenal cortisol insufficiency (ACI), a rare metabolic disorder. The study aims to define neurocognitive function in these ACI subtypes compared to healthy controls using standardized cognitive assessments and patient-reported outcomes. This research seeks to address knowledge gaps regarding the effects of cortisol dysregulation on brain function and neurocognitive impairment in ACI, which can have debilitating life-long symptoms despite standard treatment. The award period runs from Sep 15, 2025 to Aug 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $419.3k | 9/8/25 |