Project Grant R01AG092600
- Federal Grant Award Summary The National Institute on Aging awarded a $293,454 Project Grant to the University of Wisconsin-Milwaukee (awarded January 15, 2026, with completion targeted for December 31, 2030) under the Aging Research program (CFDA 93.866). This research project investigates how advancing age affects memory generalization and integration abilities—the cognitive capacity to synthesize disparate experiences into cohesive knowledge and informed decision-making. The primary...
- Federal Project Grant Award Summary The National Institute on Aging awarded a $749,108 Project Grant to the University of California, Irvine on May 15, 2025, under the Aging Research program (CFDA 93.866) to conduct research examining the relationship between memory failures and decision-making impairment in older adults through May 2030. The project delivers integrated computational and neuroscientific research services designed to understand how different types of memory—including item memory,...
- Federal Grant Award Summary Northeastern University received a $705,385 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective April 1, 2025, through August 31, 2030. The grant funds research titled "Mediators and Moderators of Executive Function Training in Older Adults," which aims to improve the rigor and reproducibility of scientific evidence regarding cognitive training interventions for older adults at risk for Alzheimer's...
- Federal Grant Award Summary The National Institute on Aging awarded a $2,631,670 Project Grant to Washington University (Award Date: September 1, 2025; Completion Date: August 31, 2029) under the Aging Research program (CFDA 93.866) to investigate age-related deficits in episodic memory for both content and structure of naturalistic events. The research will deliver scientific findings examining how aging distinctly affects memory representations and their relationship to dysfunction in...
- Federal Project Grant Award Summary Oregon Health & Science University has been awarded $471,885 by the National Institute on Aging under the Aging Research program (CFDA 93.866) to conduct a two-year research project (Award Date: June 1, 2025; Completion Date: May 31, 2027) investigating the mechanisms by which hyaluronan protects brain vascular endothelial cells from ferroptosis. The research addresses vascular contributions to cognitive impairment and dementia (VCID), the second leading...
- Federal Project Grant Award Summary Oregon Health & Science University (OHSU) received a $108,512 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) on March 6, 2025, with a completion date of September 29, 2028. The award funds basic and translational research investigating the mechanisms by which endothelin-1 (ET-1) mediated ischemic vascular dysfunction contributes to Alzheimer's disease (AD) pathology and cognitive decline. The...
- Federal Grant Award Summary The National Institute on Aging awarded a $2.49 million Project Grant to the University of California, Irvine under the Aging Research program (CFDA 93.866) on September 15, 2025, with a completion date of August 31, 2029. This award supports fundamental research investigating circuit vulnerability of the lateral and medial entorhinal cortices in tauopathy models relevant to Alzheimer's disease (AD). The project will utilize two tau mouse models to identify entorhinal...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Washington a $3.08 million Project Grant effective September 1, 2025, through August 31, 2029, under the Aging Research program (CFDA 93.866). This award supports the development of statistical machine learning methodologies and connectome-based biomarkers to enable early detection of Alzheimer's disease and related dementias (ADRD). The research addresses a critical gap in current diagnostic...
- Federal Project Grant Award Summary The University of Florida, Division of Sponsored Research, received a $126,640 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 1, 2025, with a completion date of May 31, 2030. This research initiative delivers a comprehensive scientific investigation aimed at identifying an optimal and robust measure of allostatic load (AL)—a physiological indicator of cumulative wear and tear—and...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded The Washington University a $1.85M project grant effective June 1, 2025, through March 31, 2030, under the Aging Research program (CFDA 93.866). The research initiative, titled "First In Last Out: How Development Informs Neurodegeneration," investigates the biological mechanisms linking early brain development to Alzheimer's disease (AD) pathology in later life. The project will deliver empirical research...
The University of Oregon received a $303,163 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 15, 2026, with completion scheduled for January 31, 2031. This research initiative investigates the role of conjunctive representations in cognitive control, learning, and aging—specifically how the cognitive system maintains stable thoughts and action plans while remaining flexible enough to adapt to changing circumstances. The project addresses a fundamental gap in understanding how individuals achieve context-appropriate balance between cognitive stability and flexibility, with implications for explaining age-related declines in cognitive functioning and variations in mental health outcomes. The research employs novel electroencephalographic (EEG) recording methods to track how the human cognitive system relies on different types of mental representations—conjunctive representations that integrate multiple action elements versus basic-level representations that enable greater flexibility and generalization. By elucidating the mechanisms underlying cognitive control and the balance between representational types, this project will contribute to NIA's mission of understanding the aging process and age-related cognitive disorders, with potential applications for preventing and treating conditions affecting cognitive function in older adults and informing interventions for mental health and neurological disorders characterized by cognitive control deficits.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $303.2k | 2/3/26 |