Project Grant R01AG089671
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a $3.26 million Project Grant to the University of Maryland, Baltimore on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate olfactory dysfunction as a predictor of fine particulate matter (PM2.5) exposure progression to dementia. The research will be conducted over a 47-month period (September 2025 through August 2029) and will deliver comprehensive scientific research aimed at...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a $5.16 million Project Grant to the University of California, Davis for research under the Aging Research program (CFDA 93.866), effective September 1, 2025 through August 31, 2029. This research initiative examines the relationship between environmental exposures and brain health, particularly as they relate to Alzheimer's disease and related dementias (ADRD). The project will deliver empirical research...
- Summary The National Institute on Aging (NIA) awarded a $18.3 million Project Grant to Columbia University's Health Sciences Division, effective February 1, 2026 through January 31, 2030, under the Aging Research program (CFDA 93.866). The grant supports comprehensive research investigating metal exposures and their association with Alzheimer's disease and related dementias (AD/ADRD) risk in diverse U.S. populations. Columbia will leverage two established NIH-funded cohort studies—the...
- Federal Project Grant Award Summary The University of Chicago received $1,096,231 in funding from the National Institute on Aging under the Aging Research program (CFDA 93.866) for a project grant awarded April 1, 2025, with a completion date of January 31, 2029. The award supports development of the Computerized Adaptive Test for Cognition (CAT-COG), a novel computer-based assessment tool designed to measure cognitive function across multiple domains. The CAT-COG will evaluate global...
- Federal Project Grant Award Summary The University of Montana received a $3.04 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 15, 2025, with a completion date of September 14, 2029. This research initiative investigates the role of neighborhood social exposome dynamics—the holistic social, psychosocial, and sociodemographic exposures at individual and contextual levels—in risk and resilience to Alzheimer's Disease...
- Federal Grant Award Summary The University of Southern California received a $4.06 million Project Grant from the National Institute on Aging (part of the National Institutes of Health) under the Aging Research program (CFDA 93.866), awarded on September 15, 2025, with completion scheduled for August 31, 2029. This research project will investigate the impact of circulating levels of endocrine disrupting persistent organic pollutants on cognition, brain activity, and Alzheimer's disease (AD)...
- Federal Project Grant Award Summary The University of South Florida received a $1.70 million project grant awarded September 22, 2025, by the National Institute on Aging under the Aging Research program (CFDA 93.866) to conduct transcriptome-wide mapping of the brain M6A methylome in Alzheimer's disease. The award, extending through May 31, 2030, supports comprehensive research utilizing novel technologies for N6-methyladenosine (M6A) profiling at base-resolution to create the first...
- Federal Project Grant Award Summary Northwestern University received a $3.13 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded September 1, 2025, with completion targeted for August 31, 2029. The award funds a secondary data analysis research initiative investigating the relationships among personality traits, interpersonal stress, cognitive decline, and Alzheimer's disease and related dementias (ADRD) across the lifespan....
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $6.67 million to the University of Illinois under the Aging Research program (CFDA 93.866) for a four-year project (September 1, 2025 – August 31, 2029) to develop small molecule ligands targeting pathological tau signaling in Alzheimer's disease and related dementias. The research addresses a critical unmet need by identifying compounds that block the tau phosphatase activating domain (PAD), preventing the...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $127,224 to the University of California, San Diego on October 24, 2025, under the Aging Research program (CFDA 93.866) to support scientific investigation into the pathological mechanisms of Alzheimer's disease (AD). The project, which extends through August 31, 2028, will elucidate the role of s-nitrosylated phospholipase D3 (SNO-PLD3) in microglial and neuronal pathophysiology associated with AD. Specifically,...
The University of Chicago received a $2.59 million Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 15, 2026, with completion targeted for December 31, 2030. The grant supports the Pathology, Alzheimer's and Related Dementias Study (PARDOS) APEX initiative, which investigates the association between environmental pollution exposure—specifically particulate matter and metals—and Alzheimer's disease and related dementias (AD/ADRD) clinical and pathological traits. The research leverages an established AD/ADRD cohort infrastructure to examine 2,500 deceased Brazilian individuals of European and African ancestry from the São Paulo region. The project delivers comprehensive research services and scientific outputs focused on understanding how environmental toxicants accumulate across the human lifespan and contribute to neurodegeneration. Aim 1 measures toxicant levels in lung, bone, brain, and tooth tissues to establish relationships between lifelong pollution exposure and AD/ADRD neuropathological traits. Aim 2 characterizes pollutant deposits at the subcellular level in brain regions critical to AD/ADRD pathology, including the olfactory bulb and dorsolateral prefrontal cortex. This research addresses critical knowledge gaps regarding early-life and cumulative environmental exposures while expanding diversity representation in dementia research through inclusion of underrepresented ancestral populations, thereby enabling future policy and therapeutic interventions to prevent or mitigate AD/ADRD development.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.6m | 2/10/26 |