Project Grant RF1AG094591
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $150,889 project grant to the West Virginia University Research Corporation. The project, titled "PERSONALITY AND MORTALITY RISK IN ADULTHOOD: BEHAVIORAL AND PHYSIOLOGICAL MECHANISMS", seeks to identify how personality traits influence health behaviors and physiological processes that impact longevity. The research will analyze data from over 44,000 participants to examine how...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $344,164 project grant to Northwestern University to develop "M4: Modules on Advanced Methodology When Modeling Multinational Data." The primary objectives are to: 1) create a training program in large-scale data analysis for the next generation of researchers, 2) instruct trainees on protective behavioral and social factors related to Alzheimer's disease and related dementias...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $245,434 project grant to Wake Forest University Health Sciences (WFUHS) to examine the associations between early and later-life stress on later-life cognition and plasma biomarkers of Alzheimer's disease and related dementias (ADRD). The study aims to investigate how stress experienced across the lifespan, as well as perceived psychological stress, may impact cognitive decline and...
- The Project Grant titled "The Role of Neighborhood Social Exposome Dynamics in Risk and Resilience to Alzheimer's Disease and Related Dementias" was awarded by the National Institute on Aging (NIA), under CFDA Program 93.866 - Aging Research. The $3,039,714 grant, with a performance period from September 15, 2025 to September 14, 2029, will investigate the pathways between 30 years of neighborhood-level social exposome change, individual modifiable Alzheimer's disease and related...
- This Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) is supporting the development of a "Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer's Disease and Longevity". The $802,034 award aims to conduct multi-modal analyses of genetics, multi-omics data, cross-species protein interactome networks, and human brain-specific functional genomic data to identify...
- This federal Project Grant award of $203,278.00, provided by the National Institute on Aging under the Aging Research program (CFDA 93.866), will fund research to understand the behavioral and neurobiological mechanisms underlying age-related shifts in motivation and their impact on daily life activity participation in older adults. The research will employ a multilevel, multimodal approach, utilizing behavioral, psychophysiological, neuroimaging, and naturalistic assessment methods to...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $705,385 to Northeastern University to conduct a large-scale study investigating mediators and moderators of executive function training in older adults. The study aims to improve the rigor and reproducibility of research on cognitive plasticity in older adults, many of whom are at risk for Alzheimer's disease and related dementias. The study will collect data from 1,250 older adults aged 60+ to...
- This federal Project Grant award of $459,250.00 from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) is focused on investigating the impact of stress and resilience on the longitudinal trajectories of Alzheimer's disease (AD)-related brain pathology and cognitive function. The research aims to elucidate the mechanisms by which stress may predispose individuals to long-term cognitive changes and the development of AD. The awardee, The General Hospital...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $167,940 project grant to The Children's Hospital Corporation (Boston Children's Hospital) to elucidate the neuronal mechanisms underlying cognitive resilience to Alzheimer's disease. The project, awarded on August 15, 2025, aims to (1) determine if the MEF2 transcription factors mediate survival of specific neuronal subtypes vulnerable to Alzheimer's pathology, (2) assess whether...
- This federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) provides $2,300,176 to Florida State University (FSU) to investigate how the personality trait of interpersonal conscientiousness supports cognitive health and lowers the risk of dementia. The research aims to identify the clinical, behavioral, psychological, and relational mechanisms by which interpersonal conscientiousness protects cognition, both in laboratory assessments and in...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), will provide $3,132,978 to Northwestern University to conduct a secondary analysis of data from multiple long-term observational studies on aging. The goal is to investigate the relationships between personality traits, interpersonal stress, cognitive aging, and the risk of Alzheimer's disease and related dementias (ADRD). The research will examine how changes in personality and stress over the life course are associated with cognitive decline and ADRD, while also exploring potential behavioral and physiological mediators and the moderating effects of age and socioeconomic status. The project will leverage the expertise of the research team to harmonize key variables across the data sources and identify socioeconomic disparities in cognitive health outcomes. The award period is from September 1, 2025, to August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.1m | 8/29/25 |