This federal Project Grant award from the National Institute on Aging (NIA) under CFDA 93.866 - Aging Research provides funding to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop EEG biomarkers (EDSs) for predicting the risk of dementia and monitoring cognitive decline in older adults.
The $134,730 award will support a research project that leverages deep learning and nonlinear EEG analysis to extract prognostic features from overnight EEG data collected across four national cohort studies. The objectives are to construct EDSs from EEG measures, examine their longitudinal changes and association with cognition, and combine them with genetic factors to improve dementia prediction. Exploratory work will also assess links between the EDSs and non-cognitive outcomes like sleep/circadian disturbances and disability risk. This research aims to deliver a cost-efficient, non-invasive tool for early dementia prediction and monitoring.
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