The National Institute on Aging (NIA) awarded a $3,699,536 Project Grant under the Aging Research federal grant program (CFDA 93.866) to the University of Southern California (USC) to investigate the relationship between education and Alzheimer's disease and related dementias (ADRD). The grant will leverage the International Geroscience Environment and Mild Traumatic Brain Injury Study (IGEMS) consortium of longitudinal twin studies to examine how country, birth cohort, and gender disparities...
This $729,567 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a research study investigating the causal effects of childhood school quality and infectious disease exposure on adult health and longevity. The study aims to construct a new individual-level dataset linking early life environmental factors to long-term health outcomes for large samples of Black and White Americans. Specific objectives include:
Estimating the causal impacts of...
The National Institute on Aging (NIA) awarded a $4,444,978 Project Grant under the Aging Research (CFDA 93.866) federal grant program to the Regents of the University of Michigan to conduct research on later-life cognitive reserve and resilience among older adults with and without formal education in India. The primary goals are to 1) compare the contributions of brain pathology measures to cognition between older adults with and without formal education, 2) evaluate the roles of employment,...
This National Institutes of Health National Institute on Aging project grant award of $860,772 to Bowling Green State University will fund research and training from June 2022 through May 2025 under the Aging Research program (CFDA 93.866). The university will evaluate the relationship between adult children's education levels and parental risk of Alzheimer's disease and related dementias using Health and Retirement Study panel data. Researchers will compare conceptualizations of offspring...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $319,000 to Brown University to conduct research on cognitive aging. The key objectives are to:
Identify a latent variable estimate of general cognitive performance in the Children of the Depression (CODA) cohort of the Health and Retirement Study (HRS).
Determine the pace of normative cognitive aging in standard deviations per year, both unadjusted and adjusted for...
This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $276,621.19 to the University of California, San Francisco (UCSF) to investigate the impact of attending Historically Black Colleges and Universities (HBCUs) on later-life cognition and Alzheimer's disease outcomes in Black adults.
The study will leverage national panel datasets to evaluate the causal effects of HBCU attendance, proximity, and funding policies compared to predominantly white...
This federal Project Grant award of $205,000 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports the development of a Summer Research Education Program for Promoting Computational Neuroimaging Technology in Alzheimer's Disease (AD) and AD-Related Dementias (ADRD). The program aims to address the urgent need for a capable workforce with computational neuroimaging skillsets by providing high school students with a hybrid curriculum, hands-on tutorials, and a cloud-based...
This federal Project Grant award of $122,756.00 from the National Institute on Aging (CFDA Program 93.866 Aging Research) aims to enhance the understanding of modifiable risk factors and their impacts on racial/ethnic disparities in cognitive aging during midlife. The University of California, San Francisco (UCSF) will leverage existing longitudinal cohort studies to create a diverse midlife cohort, determine the longitudinal association between modifiable risk factors and racial/ethnic...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $794,978 to the University of Pittsburgh to conduct a longitudinal study on the relationship between socioeconomic disadvantage, accelerated epigenetic aging, and cognitive decline over a midlife period. The key products and services to be delivered under this award include:
The study will leverage the Deeply Phenotyped Longitudinal Adult Health and Behavior Project to examine the...
This $174,242 Project Grant award under the National Institute on Aging's Aging Research program (CFDA 93.866) aims to study the prefrontal microcircuit changes in the brain during healthy aging and Alzheimer's disease progression. The project will integrate empirical in vivo calcium imaging recordings, computational simulation modeling, and calcium imaging-based neural decoding methods to determine the impacts of normal aging and Alzheimer's-related pathologies on the prefrontal cortex...
This $1,834,298 five-year Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund a study to evaluate the causal effects of K-12 and college educational experiences on cognitive health and functioning in older adults. The study will leverage a natural experiment provided by the National Defense Education Act (NDEA) funding from 1958-1964 to improve science, technology, engineering, mathematics (STEM), and foreign language education in K-12 schools and provide college loans for low-income STEM students. Researchers will construct a new dataset by linking historical education data with longitudinal surveys on health, education, and economic outcomes. They will use this data to estimate the causal impacts of NDEA-driven changes in educational experiences on late-life cognitive function, identify mediating pathways, and examine how effects vary by demographic factors. The study involves three sub-awards to Emory University, RAND Corporation, and Boston University, who will contribute specialized expertise in areas such as biomedical research, policy analysis, and education equity.