Project Grant R15AG074050

Award Date 6/15/22
Completion Date 5/31/26
Dollars Obligated $861K
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Ohio, USA
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The National Institute on Aging awarded a $332,135 Project Grant (CFDA 93.866 - Aging Research) to the University of California, Berkeley, with a sub-award to San Francisco State University, to investigate the relationship between early-life education availability/quality and the risk of Alzheimer's disease and related dementias (ADRD) among Black and white autoworkers. The project aims to leverage an existing occupational cohort study and link it to historical census and Medicare/Medicaid...
The National Institute on Aging (NIA) awarded a $3,699,536 Project Grant (CFDA 93.866 - Aging Research) to the University of Southern California (USC) to investigate the relationship between education and Alzheimer's disease and related dementias (ADRD). The goal is to clarify the role of educational inequalities across countries, birth cohorts, and gender in ADRD risk. Key products/services include: Leveraging the IGEMS consortium of longitudinal twin studies to examine how country, birth...
This Project Grant award, titled "LONG-TERM EFFECTS OF EDUCATIONAL INVESTMENTS ON COGNITIVE HEALTH," is funded by the National Institute on Aging (CFDA 93.866 Aging Research program) in the amount of $3,519,439. The award period runs from August 1, 2024 to April 30, 2029. The grant aims to evaluate the causal effects of K-12 and college educational experiences, particularly in STEM and foreign language curricula, on late-life cognitive function and dementia risk. The project will...
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This Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) provides $769,710 to the University of California, Los Angeles (UCLA) to study the impact of upward mobility on indicators for Alzheimer's disease (AD) risk in young adulthood, with a focus on examining sex as a moderating factor. The key products and services to be delivered under this 5-year award include: Identifying the effect of mobility opportunity on general cognitive ability in young...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The Leland Stanford Junior University (Stanford University) in the amount of $121,550 will support research to examine the effects of federal, state, and local governmental investments in early life on midlife cognition and later-life risk of Alzheimer's disease and related dementias (AD/ADRD). The research aims to (1) assess if county-level investments in legal systems or K-12 education during...
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This federal Project Grant award in the amount of $424,184 is funded by the National Institute on Aging (CFDA 93.866 - Aging Research) to study racial and ethnic disparities in access to Alzheimer's Special Care Units (SCUs) in nursing homes and the impact of SCU access on health outcomes. The key objectives are to: 1) Examine disparities in SCU access among Black and Hispanic residents with Alzheimer's disease and related dementias (ADRD), 2) Understand how SCU access contributes to disparities...
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OLDER ADULT DEMENTIA RISK AND OFFSPRING EDUCATION IN THE UNITED STATES - IN THE U.S., THE NUMBER OF OLDER ADULTS LIVING WITH ALZHEIMER'S DISEASE AND RELATED DEMENTIAS (ADRD) IS INCREASING. SIGNIFICANT LOSS OF MEMORY AND REASONING SKILLS CAN DESTROY QUALITY OF LIFE FOR THE INDIVIDUAL AS WELL AS THEIR FAMILY MEMBERS. HOWEVER, EDUCATION IS A PROTECTIVE RESOURCE: OLDER ADULTS WITH MORE EDUCATION EXPERIENCE LOWER ADRD RISK. THE POSITIVE ASSOCIATION BETWEEN EDUCATION AND COGNITIVE FUNCTIONING ALSO EXTENDS TO THE EDUCATIONAL RESOURCES OF FAMILY MEMBERS. THE EDUCATION OF ADULT CHILDREN MAY BE PARTICULARLY IMPORTANT GIVEN DEMOGRAPHIC TRENDS OF INCREASING LONGEVITY, DECLINING FERTILITY, AND LESS MARITAL STABILITY, ALL OF WHICH UNDERSCORE THE SALIENT ROLE OF ADULT CHILDREN IN OLDER ADULTS' FAMILY NETWORKS. THIS PROJECT WILL EVALUATE HOW, WHY, AND FOR WHOM CHILDREN'S EDUCATION IS RELATED TO THE RISK OF ADRD AMONG OLDER PARENTS. USING NATIONALLY REPRESENTATIVE PANEL DATA FROM THE U.S. HEALTH AND RETIREMENT STUDY (HRS), THIS PROJECT HAS THREE AIMS. THE FIRST AIM WILL COMPARE VARIOUS CONCEPTUALIZATIONS OF OFFSPRING EDUCATION. WHEREAS PRIOR WORK HAS CONSIDERED HIGHER LEVELS OF CHILDREN'S EDUCATION AS A HEALTH BENEFIT, LESS IS KNOWN ABOUT THE MEANING OF LOWER LEVELS OF OFFSPRING SCHOOLING FOR PARENTS' HEALTH. IN ADDITION, ASSESSING WHETHER "THRESHOLD" (E.G., THE EDUCATION LEVEL OF THE HIGHEST OR LEAST-EDUCATED CHILD) VERSUS "CUMULATIVE" (E.G., THE SHARE OF HIGHLY-EDUCATED CHILDREN) MEASURES OF CHILDREN'S OFFSPRING EDUCATION BETTER PREDICT ADRD RISK WILL HELP CLARIFY HOW OFFSPRING EDUCATION IS CORRELATED WITH PARENTS' BRAIN HEALTH. THE SECOND AIM WILL IDENTIFY EXPLANATORY PATHWAYS (INTERGENERATIONAL SUPPORT AND PARENTAL HEALTH BEHAVIOR AND OUTCOMES) BETWEEN CHILDREN'S EDUCATION AND PARENTAL ADRD RISK. THE PROJECT'S THIRD AIM WILL INVESTIGATE WHETHER THE RELATIONSHIP BETWEEN CHILDREN'S EDUCATION AND PARENTS' ADRD RISK DIFFERS ACROSS KEY SUBGROUPS, INCLUDING BY RACE, GENDER, AND SOCIAL CLASS. THIS WORK WILL HAVE A POSITIVE IMPACT BY VERTICALLY EXTENDING RESEARCH ON DISPARITIES TO INCORPORATE A FAMILY AND LIFE COURSE PERSPECTIVE THAT FOCUSES ON THE ARRAY OF RESOURCES INDIVIDUALS DRAW ON TO PROTECT AND ENHANCE THEIR COGNITIVE HEALTH IN LATER LIFE. THUS, THE GOALS OF THIS PROJECT ALIGN WITH THE RESEARCH PRIORITIES OF THE NIA DESCRIBED IN ITS STRATEGIC PLAN FOR RESEARCH ON AGING IN THE 21ST CENTURY. CONSISTENT WITH THE R15 AWARD MECHANISM, WE WILL MENTOR AND TRAIN UNDERGRADUATE AND GRADUATE STUDENTS IN THE RESEARCH PROCESS WHERE THEY WILL LEARN DATA MANAGEMENT AND ANALYTICAL SKILLS, WRITING AND COMMUNICATION SKILLS, AND GAIN OPPORTUNITIES TO PRESENT RESEARCH FINDINGS LOCALLY, REGIONALLY, AND NATIONALLY. THIS PROJECT WILL ENHANCE THE RESEARCH ENVIRONMENT AT BOWLING GREEN STATE UNIVERSITY AND HELP LAUNCH THE NEXT GENERATION OF POPULATION HEALTH SCIENTISTS.

Posted 6/3/22, 12:00 AM