Project Grant R01AA032115
- The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $474,223 on May 11, 2026, under the Alcohol Research Programs (CFDA 93.273) to elucidate brain region- and cell-specific mechanisms of alcohol-induced developmental neurotoxicity and develop precision interventions targeting neuroprotection. The research addresses fetal alcohol spectrum disorder (FASD), which contributes significantly to intellectual disabilities with a prevalence rate of 1-5% in the...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $226,406 on August 10, 2026, under the Alcohol Research Programs (CFDA 93.273) to investigate pain sensitivity, alcohol-induced analgesia, and heavy drinking in individuals with opioid use disorder. The research addresses a critical gap in understanding mechanisms that drive concurrent alcohol and opioid use, which occurs at rates 13 times higher in individuals with opioid use disorder compared to the...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $1,771,875 under the Alcohol Research Programs (CFDA 93.273) on August 4, 2026, for research into the novel mechanism of nuclear histone deacetylase 4 (HDAC4) in early-life stress-induced alcohol consumption, preference, and tolerance in offspring. The research develops a mouse model using offspring born to dams that experienced prenatal restraint stress during pregnancy to investigate how early-life...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $1,390,966 on September 18, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a randomized, double-blind, placebo-controlled clinical trial testing suvorexant as a novel therapeutic for alcohol use disorder and stress-related drinking. The trial will enroll 250 treatment-seeking individuals with current alcohol use disorder and randomize participants to eight weeks of 10 milligrams nightly...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $1,188,981 on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273) to mechanistically characterize JNK2A variants in alcohol-caused heart failure. The research investigates how long-term excessive alcohol consumption drives alcoholic cardiomyopathy through alcohol-activated JNK2 regulation of the SERCA2 calcium pump, moving from adaptive cardiac remodeling to maladaptive suppression of...
- The National Institute on Alcohol Abuse and Alcoholism awarded The Research Foundation For The State University Of New York $632,070 on September 16, 2025, under the Alcohol Research Programs (CFDA 93.273) to conduct a Phase 2 efficacy trial of a friend-based motivational interviewing intervention designed to reduce alcohol-involved sexual assault risk among college women. The award funds a randomized controlled trial examining the efficacy of the PAIRS (Protecting Allies in Risky Situations)...
- The National Institute on Alcohol Abuse and Alcoholism awarded Arizona State University $650,613 on May 11, 2026, under the Alcohol Research Programs (CFDA 93.273) to support longitudinal research examining within-person risk factors for sexually aggressive behavior in college men, with performance through January 31, 2031, in Tempe, Arizona. The project disaggregates between-person from within-person risk factors for contact and non-contact sexual aggression using a longitudinal burst design...
- The National Institute on Alcohol Abuse and Alcoholism awarded Yale University $100,228 under the Alcohol Research Programs (CFDA 93.273) on October 27, 2026, to investigate the neurobiological mechanisms underlying the co-occurrence of alcohol use disorder and post-traumatic stress disorder. The project examines how stress exposure disrupts excitation-inhibition balance in the medial prefrontal cortex, driving increased alcohol consumption and heightened motivation for alcohol use. Using single...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $167,500 in Project Grant funding to the University of Massachusetts Medical School on September 17, 2025, through the Alcohol Research Programs (CFDA 93.273) for a research study investigating sex differences in excessive alcohol use patterns across young adulthood and middle age. The research will utilize longitudinal data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine how...
- The National Institute on Alcohol Abuse and Alcoholism awarded the University of Missouri System $1,413,058 on September 10, 2025, under the Alcohol Research Programs authority (CFDA 93.273) to conduct a longitudinal ecological momentary assessment study of alcohol consumption patterns and contexts across the transition to legal drinking age. The study employs a burst design to track 20-year-olds sampled from Missouri driver's license records (birth years 2005–2008, rural and small metro...
The National Institute on Alcohol Abuse and Alcoholism awarded The Ohio State University $706,409 under the Alcohol Research Programs (CFDA 93.273) on September 1, 2026, to examine the neurobiological mechanisms linking sexual assault victimization to alcohol use disorder risk in college-aged adults. The study will recruit 220 heavy-drinking participants aged 21–29, divided into two groups: those with a history of sexual assault and those without. Researchers will conduct three laboratory sessions per participant using the no-predictable-unpredictable threat paradigm to measure reactivity to uncertain threat, combined with intravenous alcohol administration, ecological momentary assessment, and transdermal alcohol biosensing. The research tests a mechanistic model proposing that sexual assault victimization increases neurobiological sensitivity to unpredictable stress or threat, which heightens sensitivity to alcohol's anxiolytic effects and drives heavy drinking. The multimodal project integrates converging research programs from two multiple principal investigators. The award runs through August 31, 2031, with place of performance in Columbus, Ohio. This is a Project Grant (assistance type), provided directly to the recipient institution by NIAAA. The program supports development of fundamental knowledge applicable to improved treatment methods and prevention strategies for alcoholism and alcohol-related problems, with awards typically limited to five years and subject to competing renewal.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $706.4k | 8/27/26 |