Project Grant R01AA032052
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of California, San Diego a $2.25 million Project Grant (CFDA 93.273 – Alcohol Research Programs) on September 20, 2025, for a four-year research initiative extending through August 31, 2029. The award funds longitudinal magnetic resonance imaging (MRI) studies examining brain features associated with alcohol use disorder (AUD) in a cohort of 100 genetically diverse outbred rats...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a Project Grant of $919,414 to The Medical University of South Carolina on September 5, 2025, under the Alcohol Research Programs (CFDA 93.273). This award supports a five-year research initiative (through May 31, 2030) investigating the role of astrocytes in alcohol use disorder (AUD), specifically examining how chronic intermittent alcohol exposure alters astrocyte physiology, structure, and gene...
- Federal Grant Award Summary Funding Agency: National Institute on Alcohol Abuse and Alcoholism (NIAAA) Federal Grant Program: Alcohol Research Programs (CFDA 93.273) Award Amount: $559,180 Award Date: September 1, 2025 Project Period: September 1, 2025 – June 30, 2030 Awardee: RTI International (Research Triangle Institute), Research Triangle Park, North Carolina RTI International will conduct multi-omic research to identify neurobiological factors underlying alcohol use disorder (AUD) with...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Pennsylvania a Project Grant of $727,664 (awarded May 1, 2026; completion February 28, 2031) under the Alcohol Research Programs (CFDA 93.273) to conduct multi-omics spatial analysis of ethanol responsiveness in single mouse brain neurons and astrocytes. The research project delivers comprehensive genomic characterization of alcohol-induced changes in brain cells within their...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $551,464 to the Palo Alto Veterans Institute for Research on September 20, 2025, under the Alcohol Research Programs (CFDA 93.273). This Project Grant supports a randomized, double-blind, sham-controlled mechanistic trial investigating the efficacy of deep transcranial magnetic stimulation (DTMS) as a neuromodulation treatment for alcohol use disorder (AUD). The research will enroll 100 adults with...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Pennsylvania a Project Grant of $115,307 under the Alcohol Research Programs (CFDA 93.273) for the period September 1, 2025, through August 31, 2027. This K99/R00 career development award supports research examining the neuropharmacological effects of the ketogenic diet (KD) on alcohol intoxication in both healthy individuals and those with alcohol use disorder (AUD). The research...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $497,962 to the University of California, San Diego on September 15, 2025, under the Alcohol Research Programs (CFDA 93.273) to support a three-year research project through August 31, 2028. The award funds research investigating the role of gut microbial ethanol production in alcohol use disorder and alcohol-associated liver disease. The project will characterize the gut microbiota of...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded The Leland Stanford Junior University a Project Grant totaling $597,138 beginning May 1, 2026, and concluding March 31, 2031, under the Alcohol Research Programs (CFDA 93.273) federal grant program. The award supports research investigating the neural mechanisms linking extended amygdala arousal circuitry to alcohol-induced sleep disruption and the reciprocal relationship between poor sleep...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of North Carolina at Chapel Hill a Project Grant totaling $444,576 under the Alcohol Research Programs (CFDA 93.273) to conduct a preclinical research screening pipeline evaluating glucagon-like peptide-1 receptor agonist (GLP-1RA) compounds for potential efficacy in treating alcohol use disorder (AUD). The research project, initiated May 1, 2026 and concluding January 31,...
- Federal Grant Award Summary Texas A&M University System Health Science Center received a $635,002 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), effective June 15, 2026, with completion targeted for April 30, 2031. The award funds research investigating cholinergic modulation of striatal circuits in alcohol use disorder (AUD). The project will deliver scientific research products examining how chronic...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded The Regents of the University of California, San Francisco a Project Grant totaling $613,750 (award date: June 15, 2026; completion date: April 30, 2031) under the Alcohol Research Programs (CFDA 93.273) to conduct biomedical research examining the relationship between brain glucose metabolism and alcohol use disorder (AUD). The research investigates how alcohol activates the mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway in dopamine D1 receptor-expressing neurons within the nucleus accumbens, leading to impaired glycolysis and increased heavy alcohol consumption. The study utilizes animal models and employs molecular biology techniques to analyze how this pathway suppresses aldolase A translation and lactate production while examining potential therapeutic interventions, including lactate administration and microRNA manipulation, to restore normal glucose metabolism and reduce alcohol-seeking behavior. This research directly supports NIAAA's mission to develop improved treatment methods and prevention strategies for alcoholism by establishing fundamental knowledge of the metabolic mechanisms underlying AUD. The work combines preclinical investigation with translational potential, examining how disrupted energy metabolism in specific brain regions contributes to alcohol dependence and exploring evidence-based approaches to reverse these metabolic dysfunctions as a treatment strategy.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $613.8k | 6/16/26 |