Project Grant R00HD110645
- This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to functionally and architecturally characterize the role of RFamide-related peptide (RFRP) neurons in controlling the timing of puberty onset. The $126,462 award to the University of California, San Diego will leverage state-of-the-art molecular genetic tools to delineate...
- This Project Grant award of $799,756 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund a randomized controlled trial to assess whether weight loss and positive health behavior change in the prepubertal period can slow pubertal onset in girls at risk for accelerated pubertal development. The study will enroll 240 prepubertal girls at risk for earlier puberty based...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $746,999 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Broad Institute, Inc. to characterize the genetic etiology of delayed puberty and rare congenital forms of infertility. The research project aims to: 1) Define the spectrum of genomic variants contributing to idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome...
- This Project Grant award of $747,000.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to evaluate breast pumping protocols and elucidate the molecular and cellular mechanisms underlying enhanced milk production. The research aims to address critical issues around suboptimal breastfeeding practices, which result in significant public health...
- This Project Grant award of $157,000.00, provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a longitudinal, prospective study investigating the relationship between pregnancy stress, maternal mental health symptoms, sex steroid hormones, and postpartum maternal sensitivity. The study aims to determine the individual and coordinated trajectories...
- This Project Grant award of $170,640 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to investigate the role of the FGFR1 signaling pathway in the intersection between reproduction and metabolism. The primary objectives of this 5-year research project are to: (1) conduct a recall-by-genotype study and in-depth neuroendocrine and metabolic phenotyping in...
- This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop an early life phenotyping framework for very preterm infants. The research aims to create 'perinatal phenotypes' by integrating variables such as reason for preterm birth, intrapartum care, and neonatal presentation, and then determine how these phenotypes contribute to...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), will provide $719,892 to New York University to conduct research on the relationship between infant exposure to phthalates and bisphenols and reproductive development during the "minipuberty" period in the first six months of life. The project will enroll 480 infants in the ongoing NYU Children's Health and Environment...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $256,008 to Teachers College Columbia University to study the associations between maternal stress, infant epigenetics, and behavioral/cognitive development in early childhood. The research project aims to integrate epigenetic aging as a biomarker to explain the relationship...
- This $659,035 Project Grant award from the National Institute of Child Health and Human Development (NICHD), part of the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research on the role of thyroid hormone as a key regulator of neurodevelopment during early life iron deficiency. The grant aims to investigate the mechanistic basis for the interactions between iron and thyroid hormone during brain development. The research will focus on how...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund a $249,000 research project to examine the role of "minipuberty" - the reactivation of the hypothalamic-pituitary-gonadal axis in infancy - on growth, breast development, and pubertal timing in girls. The principal investigator will use longitudinal data from the Infant Feeding and Early Development (IFED) study to investigate associations between sex steroid concentrations during minipuberty and later outcomes related to breast development and linear growth velocity. The project will also conduct a follow-up of the IFED cohort as they transition through puberty. This research aims to improve understanding of the critical minipuberty period and its effects, which could inform interventions to address the trend of earlier pubertal onset in girls, which is linked to adverse health consequences.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.0k | 8/28/25 |