Project Grant R00HD108389
- The federal Project Grant award of $429,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to characterize placental extracellular vesicles (EVs) throughout human pregnancy. The goal is to develop novel methods to image, count, isolate, and validate placental cell- and size-specific EVs from maternal blood, in order to monitor placental...
- This federal Project Grant award, funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), is supporting research on the role of decidual extracellular vesicles in mediating placental insufficiency. The $654,671 award, which commenced on August 1, 2025 and is scheduled for completion by April 30, 2030, is being conducted by the awardee, Yale University. The key...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- This Project Grant award, totaling $601,499 and spanning from June 2025 to May 2030, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research focused on understanding how maternal obesity during pregnancy alters mitochondrial function in the offspring, which is linked to the later development of obesity and metabolic syndrome. Key objectives include:...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This federal Project Grant award of $719,141, awarded on August 11, 2025 by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support a longitudinal study comparing maternal prenatal distress effects between in-vitro fertilization (IVF) donor oocyte/embryo and non-donor oocyte pregnancies. The study aims to rigorously test the developmental origins of health and disease (DOHAD)...
- This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) provides $164,561.00 to the University of California, Davis to investigate the relationship between prenatal exposure to endocrine disrupting chemicals (EDCs) and the development of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in children. The research aims to evaluate the potential mediating role of cytokines and DNA methylation in this...
- This $2,267,819 Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Abuse and Addiction Research Programs) will fund research by the University of Washington to characterize extracellular vesicle (EV) profiles in healthy pregnancies and those complicated by opioid use disorder. The goal is to identify biomarkers in placental EVs and fetal brain/central nervous system EVs that could predict an infant's risk of developing neonatal opioid withdrawal syndrome (NOWS) and...
- This Project Grant award of $765,571 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research on placental fatty acid metabolism in gestational diabetes mellitus (GDM). The project aims to investigate sexual dimorphism in placental function and its role in adverse pregnancy outcomes associated with GDM, with a focus on understanding the effects of GDM...
- This National Science Foundation project grant award of $1,444,730 provides funding from June 1, 2022 to May 31, 2026 to The Ohio State University Office of Sponsored Programs under the Biological Sciences (CFDA 47.074) federal grant program. The award will support research investigating neuroimmune contributions to maternal care during pregnancy. The grantee aims to further understanding of how pregnancy hormones impact the expectant mother's immune system and brain function to foster...
The federal Project Grant award titled "Prenatal Extracellular Vesicles and Steroid Hormones as Biological Mechanisms Underlying Gestational Factors Associated with Neurodevelopmental Risk" was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $747,000 award, with an initial period of performance from September 1, 2025 to August 31, 2028, will support research at The Ohio State University to investigate the independent and interactive effects of prenatal maternal/fetal extracellular vesicles (EVs) and maternal/fetal steroid hormones as potential biological mechanisms underlying infant neurobehavioral and social-emotional development. The research aims to uncover early-emerging biomarkers that may serve as tools for early identification of children at risk for neurodevelopmental disorders, including autism spectrum disorder.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $747.0k | 9/8/25 |