Project Grant R00ES035109
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $379,504 to the University System of New Hampshire's Keene State College to conduct research on the tissue-specific development of toxicity in response to transgenerational chronic arsenic exposures. The key objectives are to: (1) detect tissue-specific uptake of arsenic in response to transgenerational chronic exposure; (2)...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded The Research Foundation For The State University of New York (RF-SUNY at the University at Albany) a $814,154 Project Grant under the Environmental Health program (CFDA 93.113) beginning April 1, 2026, with a completion date of March 31, 2031. This five-year award supports research investigating the interplay between the epitranscriptome and epigenome in regulating cellular responses to...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $649,193 Project Grant from the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113), effective April 1, 2026 through March 31, 2031. This award supports mechanistic research investigating how naturally occurring toxic heavy metals—specifically arsenic, cadmium, chromium, and nickel—disrupt epitranscriptomic regulation and induce pathogenesis in...
- Federal Project Grant Award Summary New York University School of Medicine received a $10.9 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 15, 2025, with a completion date of September 14, 2029. This translational research initiative investigates the accumulation of micro- and nanoplastic particles (MNPs) in mammalian tissues across the lifespan. The project addresses a critical...
- Federal Project Grant Award Summary New York University School of Medicine received a $1,124,358 project grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective August 22, 2025 through May 31, 2030. The award supports research investigating the impact of hexavalent chromium [CR(VI)] exposure on skeletal muscle differentiation and regeneration. Given that CR(VI) is widely used in industrial processes...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of New Mexico Health Sciences Center a Project Grant of $456,328 on September 15, 2025, under the Environmental Health program (CFDA 93.113) to investigate patterns of autoimmune biomarkers among Native American and Alaska Native tribal members exposed to metals, metalloids, and organochemicals. The two-year project (completion date September 14, 2027) will establish a...
- Federal Project Grant Award Summary NYU Grossman School of Medicine, in collaboration with Erasmus University Medical Center, will conduct a longitudinal life-course epidemiological study examining how prenatal and childhood exposures to environmental chemicals—specifically organophosphate pesticides, glyphosate, phthalates, and bisphenols—contribute to the development of chronic kidney disease (CKD) in children and adolescents. The research, funded by the National Institute of Environmental...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded $163,614 to the University of Illinois, effective September 1, 2025, through March 31, 2029, under the Environmental Health program (CFDA 93.113). This research project investigates lipid-based interventions to mitigate arsenic-induced neurobehavioral dysfunction through a complementary approach combining in vivo mouse studies and ex vitro microglial experiments. The research seeks to...
- Federal Project Grant Award Summary Boston University Medical Campus received a $147,486 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded November 1, 2025, with completion targeted for August 31, 2028. This research project will investigate the neurodevelopmental impacts of early-life exposure to ferroalloy metal mixtures—including manganese, lead, chromium, and copper—on adolescent cognitive...
- Federal Grant Award Summary Luxbiome Inc. received a $612,748 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 12, 2025, with completion targeted for August 31, 2026. This Phase I award supports the development of microbiome-based therapeutic solutions designed to reduce inorganic arsenic (IAS) body burden through mechanism-guided gut microbiome modulation. The project delivers two primary...
Grant Award Summary New York University School of Medicine received a $248,999 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective June 2, 2026, through May 31, 2029. The award supports research investigating the epigenetic and genetic regulation of arsenic methylation and its relationship to cardiovascular disease (CVD) risk in Native American communities. The project leverages biospecimens and longitudinal data from the Strong Heart Study and Strong Heart Family Study cohorts to identify epigenetic biomarkers of arsenic toxicity, distinguish molecular mechanisms underlying arsenic methylation phenotypes, and elucidate how microRNAs mediate the association between arsenic exposure and CVD risk. The research deliverables include scientific investigations across three primary aims: determining relationships between DNA methylation, arsenic methylation efficiency, and CVD outcomes; analyzing genetic variation effects on DNA methylation associated with arsenic metabolism; and examining microRNA roles in mediating arsenic exposure effects on methylation efficiency and CVD biomarkers. Dr. Bozack will receive mentorship from experts in environmental, molecular, and genetic epidemiology to conduct these analyses, with results intended to advance understanding of environmental health disparities affecting rural populations reliant on private well water contaminated with arsenic and to identify intervention strategies for reducing disease burden in vulnerable Native American populations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.0k | 6/5/26 |