Project Grant R01ES038329
- Federal Project Grant Award Summary The University of Texas at Austin received a $124,808 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), obligated on August 25, 2025, with a completion date of July 31, 2027. This award funds research investigating how environmental endocrine-disrupting chemicals (EDCs) disrupt cognitive and food reward processes in the brain, with particular focus on dopamine pathways...
- Federal Grant Award Summary Boston University Medical Campus received a $147,486 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded November 1, 2025, with completion targeted for August 31, 2028. The grant supports research investigating early-life exposure to ferroalloy metal mixtures—including manganese, lead, chromium, and copper—and their effects on adolescent cognitive development. The research...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health program (CFDA 93.113), awarded a $246,562 Project Grant to the Icahn School of Medicine at Mount Sinai effective May 1, 2025, with a completion date of December 31, 2027. This research initiative investigates the impact of perinatal metal mixture exposure and prenatal maternal stress on neural and cognitive constructs underlying adolescent risk-taking behaviors. The...
- Federal Grant Award Summary New York University School of Medicine received a $10.9 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded on September 15, 2025, with a completion date of September 14, 2029. The award supports translational research investigating the accumulation of micro- and nanoplastic particles (MNPs) in mammalian tissues and their health implications. The project addresses...
- Federal Project Grant Award Summary New York University School of Medicine received a $503,642 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective August 22, 2025, with a completion date of May 31, 2030. The award supports research investigating the effects of hexavalent chromium (CR(VI)) exposure on skeletal muscle differentiation and regeneration. The research addresses a significant...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded $814,154 under the Environmental Health program (CFDA 93.113) to The Research Foundation For The State University of New York at the University at Albany, effective April 1, 2026 through March 31, 2031. This Project Grant supports research investigating the interplay between the epitranscriptome and epigenome in regulating cellular responses to toxicants, with a focus on naphthalene, a major...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $749,640 Project Grant to the University of California, Davis, effective April 1, 2026 through March 31, 2031, to conduct research investigating the interplay between TET1-mediated epigenomic mechanisms and N6-methyladenosine (m6A) RNA modification in pulmonary inflammation induced by particulate matter (PM) exposure. Under the Environmental Health program (CFDA 93.113), the research...
- Federal Grant Award Summary The University of Texas Medical Branch at Galveston received a $718,775 Project Grant from the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113) to conduct research on understanding the role of gut microbiome in trichloroethene (TCE)-mediated autoimmunity. The award, obligated on April 1, 2026, with a completion date of January 31, 2031, will fund mechanistic research investigating how environmental TCE exposure...
- Federal Project Grant Award Summary Texas A&M University System Health Science Center has been awarded $2.47 million by the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113) for a four-year research project spanning September 2025 through September 2029. The award supports investigation into phthalate-induced epigenetic regulation in adipose tissues, with the principal objective of elucidating the mechanisms by which phthalate exposure—a...
- Federal Project Grant Award Summary The University of Texas at Arlington received a $605,091 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective April 16, 2026 through April 15, 2029. The award supports development of CONNECT (Cohort-Oriented Network Knowledgebase for Enhanced Collaboration), a directed knowledge graph and web-based resource that synthesizes and harmonizes environmental health...
The University of Texas Southwestern Medical Center received a $649,193 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective April 1, 2026 through March 31, 2031. This five-year research award supports mechanistic investigations into how naturally occurring heavy metals—including arsenic, cadmium, chromium, and nickel—disrupt epitranscriptomic regulation and contribute to carcinogenesis and pathogenesis in human cells. The research deliverables encompass three integrated investigative aims: (1) assessment of heavy metal effects on mRNA methylation enzymes (METTL3-METTL14), including impacts on m6A methylation patterns and their crosstalk with chromatin and DNA methylation; (2) evaluation of heavy metal influences on tRNA methyltransferase activity (METTL1) and associated AKT signaling pathways; and (3) examination of heavy metal-induced dysregulation of microRNA biogenesis through the DROSHA-DGCR8 complex, including analysis of metal-dependent crosstalk between RNA methylation and processing mechanisms. The project will generate molecular-level insights into heavy metal toxicity mechanisms affecting the epitranscriptome to inform future strategies for reducing disease burden from environmental metal exposures.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $649.2k | 4/1/26 |