Project Grant P60AA032190
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $1,593,618 Project Grant under the Alcohol Research Programs (CFDA 93.273) to establish the Center for Alcohol/HIV Innovations and Biomarker Research (CALIBER) at the University of California, San Francisco (UCSF). The goal of CALIBER is to (1) reduce the harmful effects of alcohol use on HIV prevention and HIV-associated comorbidities, (2) advance innovations in alcohol measurement, and (3) train the next generation of...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $550,417 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Texas at Austin. The grant, effective September 1, 2025 through May 31, 2030, supports research to investigate how heavy alcohol exposure in aging individuals leads to impaired microglia function, neurodegeneration, and cognitive deficits. The study aims to determine whether dysregulated neuroimmune and microglia responses are...
- The Southeast Translational Alcohol and HIV Research (STAHR) Center was awarded a $1,785,057 Project Grant by the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) to conduct three inter-related clinical trials and observational studies focused on reducing alcohol consumption and mitigating alcohol's harmful effects on cardiovascular disease risk among people living with HIV. The key objectives are to: 1) examine the association between alcohol, gut...
- This $634,829 Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) supports a research project titled "Geroprotective Precision Medicine Strategies in PWH that Use Alcohol". The project aims to identify personalized approaches to overcoming inconsistent responses to microbiota-targeted interventions and validate their capacity to offset mechanisms of biological aging in people with...
- This $527,129 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) supports research to identify biomarkers and develop novel strategies to prevent or treat inflammation-associated comorbidities in people living with HIV on antiretroviral therapy. The award recipient, Northwestern University, will conduct research to examine how glycomic alterations in circulating IgGs may contribute to HIV-associated inflammation and identify these alterations as potential...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), supports research to investigate the relationship between HIV infection, aging, and cognitive decline. The $629,712 award to SRI International aims to leverage magnetic resonance imaging (MRI) and biomarker analysis to better understand how the brain's waste clearance system, known as the glymphatic system, may contribute to heightened risk of cognitive impairment in aging...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $136,236 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Washington on January 25, 2025. The grant project aims to investigate the synergistic effects of chronic alcohol use and pathological tau expression in a preclinical model, in order to better understand the neurodegeneration processes underlying Alzheimer's disease and related dementias (ADRD). Specifically, the research will...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $468,534 to the University of Southern California to examine alcohol consumption as a modifiable risk factor for Alzheimer's disease and related dementias (ADRD). The study aims to delineate the relationship between midlife alcohol consumption and late-life ADRD diagnosis and onset, with a focus on potential sex differences. It will also test the interaction between alcohol consumption...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $105,132 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Kentucky Research Foundation. The grant, titled "Uncovering the Functional and Mechanistic Dysregulation of Monocytes After Abstinence and Post-Abstinence Drinking," will leverage a rhesus macaque model to investigate the persistent functional, transcriptional, and epigenetic changes in peripheral monocytes induced by...
- This Project Grant award from the Department of Health and Human Services' National Institutes of Health (CFDA 93.310 - Trans-NIH Research Support) provides $703,644 to the Icahn School of Medicine at Mount Sinai to investigate the drivers of accelerated aging in people living with HIV (PWH). The research aims to study the effects of HIV and antiretroviral therapy on epigenetic aging and clonal hematopoiesis, as well as examine the role of socio-behavioral factors and genetic predisposition in...
The Aging Well with HIV through Alcohol Research and Risk Reduction and Education (AWAR3E) Center is a $1,493,442 Project Grant awarded by the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 Alcohol Research Programs) on September 10, 2025. The grant supports a collaborative research initiative across four HIV cohorts to characterize "inflammaging" and associated geriatric syndromes among people with HIV. The Center will investigate novel biomarkers of inflammaging, evaluate the safety and effectiveness of potential treatments like long-acting antiretroviral therapy and GLP-1 receptor agonists, and explore how socioeconomic factors and unhealthy alcohol use impact access to these treatments. The research aims to better understand and address the unique health challenges faced by aging populations with HIV.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/25/25 | ||
| Not listed | $1.5m | 9/13/25 |