Project Grant R21AG096957
Award Date 9/15/25
Completion Date 8/31/27
Dollars Obligated $630K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
California, USA
Similar Awards
- The National Institute on Aging (NIA), through its Aging Research program (CFDA 93.866), has awarded a $534,644.00 Project Grant to Temple University - Of The Commonwealth System Of Higher Education. The grant aims to characterize how the HIV-1 virus decreases neuronal clearance, leading to the progression of HIV-associated neurocognitive disorders like motor dysfunction. Key research activities include determining the post-translational regulation of the SNAPIN protein and its impact on...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) will provide $880,000 to Old Dominion University from September 2024 through August 2026. The project aims to investigate the therapeutic effects of microglia depletion and repopulation (MGDR) on mitigating hand and neuropsychiatric symptoms in the context of chronic HIV infection. Specifically, the research will explore the impact of MGDR on brain pathology in HIV-infected mouse models, examining its...
- This Project Grant award from the National Institute on Aging (NIA), funded under the Aging Research program (CFDA 93.866), will support a study to examine the impacts of HIV stigma and gender-based stigma on cognitive function among older women living with HIV/AIDS (WLWH) in the United States. The $146,922 award, with a performance period from January 25, 2025 to July 31, 2025, will leverage data from the longitudinal Women's Interagency HIV Study (WIHS) to investigate whether social support...
- This Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) provides $1,550,462 to support a 5-year cross-sectional, longitudinal, and observational study investigating the impact of Alzheimer's disease (AD) risk genes, with a focus on APOE E4, on brain function in older Black/African American individuals living with HIV. The project aims to enroll 120 participants with HIV (60 with and 60 without the APOE E4 allele) and 80 demographically...
- This $788,121 Project Grant awarded by the National Institute on Aging (CFDA 93.866 Aging Research) will fund a 5-year cross-sectional, longitudinal, and observational study to investigate the impact of Alzheimer's disease (AD) risk genes, with a focus on APOE E4, on brain function in HIV-positive older Black/African American adults. The study aims to increase understanding of Alzheimer's disease and related dementias (ADRD) risk factors in this vulnerable population, who face an increased...
- This federal Project Grant award of $194,375.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), aims to determine the impact of persistent HIV in the central nervous system (CNS) on inflammation, brain structure and function, and cognition in people living with HIV. The primary goals are to: 1) Evaluate the specific contribution of HIV in the CNS to...
- This Project Grant award from the Department of Health and Human Services' National Institutes of Health (CFDA 93.310 - Trans-NIH Research Support) provides $703,644 to the Icahn School of Medicine at Mount Sinai to investigate the drivers of accelerated aging in people living with HIV (PWH). The research aims to study the effects of HIV and antiretroviral therapy on epigenetic aging and clonal hematopoiesis, as well as examine the role of socio-behavioral factors and genetic predisposition in...
- This federal Project Grant award, provided by the Department of Health and Human Services National Institutes of Health (CFDA 93.310 Trans-NIH Research Support program), will support a mixed-methods research study to understand the interplay of social and physical environments, loneliness, and cognition among older people living with HIV. The $123,579 award, with a performance period from June 15, 2025 to March 31, 2030, will be administered by Northeastern University. The research aims to...
- The U.S. Department of Health and Human Services National Institutes of Health (NIH) awarded a 1-year, $750,000 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to Tulane University, effective September 5, 2025. The grant supports research aimed at understanding the role of lactate and lactylation in the development and progression of HIV-related neurocognitive disorders, particularly in the context of aging among people living with HIV. Key aspects of the research...
- This $527,129 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) supports research to identify biomarkers and develop novel strategies to prevent or treat inflammation-associated comorbidities in people living with HIV on antiretroviral therapy. The award recipient, Northwestern University, will conduct research to examine how glycomic alterations in circulating IgGs may contribute to HIV-associated inflammation and identify these alterations as potential...