Project Grant P20GM156712
- The National Institute of General Medical Sciences (NIGMS) awarded a $2,490,273 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Rhode Island Hospital on August 16, 2025. The grant will fund the establishment of a Center for Biomedical Research Excellence (COBRE) at Rhode Island Hospital's Center for International Health Research, in partnership with collaborators across Rhode Island. The COBRE, titled "Translational Approaches for Pathogens of...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $423,616 Project Grant to Brown University. The grant, effective from September 1, 2025 to June 30, 2030, will support the development of integrative computational models to decode disease mechanisms and predict drug synergies in spatial transcriptomics. The research aims to uncover how the spatial arrangement of cells within tissues (cellular spatial...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $431,656 Project Grant to the University of Massachusetts to elucidate the function of ribonucleoprotein (RNP) condensates in living cells. The research aims to develop novel methods to accurately identify the RNA-binding proteins that regulate the formation and disassembly of RNP condensates, which play a crucial role in cellular function and disease...
- This $213,180 Project Grant award from the National Institute of General Medical Sciences (CFDA 93.859 - Biomedical Research and Research Training) aims to establish a Transdisciplinary Training Program in Biomedical Sciences and Bioengineering (BSBE) at the University of Rhode Island (URI). The program will bring together predoctoral graduate students and faculty from diverse disciplines, including biology, human health, neuroscience, and biomedical engineering, to provide broad...
- This federal Project Grant award of $387,500.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to investigate the evolutionary constraints on regulatory RNA at Boston College. The goal is to understand how concepts from protein evolution, such as robustness, plasticity, promiscuity, and epistasis, apply to the evolution of RNA regulators. The researchers will leverage a series of RNA...
- This federal Project Grant award for $678,000.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to understand the molecular mechanisms governing the assembly of eukaryotic ribosomes. The research aims to define the co-transcriptional assembly events and transitions towards stable post-transcriptional nucleolar assembly intermediates of ribosomal subunits, leveraging advanced...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the molecular mechanism of the VASA protein's role in regulating localized mRNA translation on the mitotic spindle during embryonic development. The $438,625 award to Brown University, spanning from August 1, 2025 to May 31, 2030, aims to: 1) identify VASA's target mRNAs and their...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to advance the design of bifunctional chelators (BFCs) for copper-based radiopharmaceuticals. The $398,750 award to Brown University aims to overcome longstanding challenges in the development of copper-based radiopharmaceuticals by improving the in vivo kinetic stability of BFCs. The research will...
- This federal Project Grant award of $459,250.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to develop a systematic approach for detecting regulatory RNAs and their functional motifs based on RNA-protein interactions. The key research objectives include: Investigating whether RNA regulates the genomic occupancies of chromatin-associated proteins (CAPs). Employing an...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) will support research into the molecular mechanisms of ribosome biogenesis by force-producing enzymes. The $392,500 award to Rutgers, The State University of New Jersey will fund a 5-year project focused on characterizing how ATP-driven mechanoenzymes sequentially convert ribosomal precursors into mature ribosomes. Key activities...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training federal grant program (CFDA 93.859), has awarded a $2,231,717 Project Grant to Brown University in Providence, Rhode Island. The grant will establish and build the COBRE Center for RNA Biology in Health and Disease at Brown University. The objective is to create a research infrastructure and academic community positioned to advance scientific discoveries in RNA biology, with a focus on understanding and treating human disease. The grant will support the research activities of junior investigators to help them transition to independent R01-funded scientists. The project aims to bring cutting-edge RNA technologies to Rhode Island and foster a collaborative service culture for implementing new RNA methodologies. The long-term goal is to build an RNA biology infrastructure that will benefit the study of human disease across the state.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.2m | 8/15/25 |