This Project Grant award, titled "EXPLOITING THERAPEUTIC VULNERABILITIES IN HEPATOCELLULAR CARCINOMA (ELEVATE)", is funded by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research). The $2,678,459 award aims to advance the understanding of molecular mechanisms regulating non-alcoholic steatohepatitis (NASH)-associated hepatocellular carcinoma (HCC) and develop novel combinatorial treatment approaches. The award supports four research projects, an administrative core, a mouse model and pathological analysis core, and a biostatistics and bioinformatics core. The projects involve experts in HCC biology, liver physiology, medicinal chemistry, cancer immunotherapy, and bioinformatics, with the goal of generating translationally relevant data to transform the management of HCC patients. The award has multiple sub-awards to the University of Virginia, Northwestern University, and the University of Iowa to support collaborative research efforts.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $2.7m | 8/1/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
FP00019911SA003S | Rector & Visitors Of The University Of Virginia | Project Grant P01CA275740 | $53.6k | 10/1/24 | |
FP00019911SA002S | Northwestern University | Project Grant P01CA275740 | $59.1k | 9/23/24 | |
FP00019911SA001S | The University Of Iowa | Project Grant P01CA275740 | $59.0k | 9/5/24 |