Project Grant P01AI187003
- Federal Project Grant Award Summary Yale University received a $105,402 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 27, 2026, with a completion date of April 15, 2029. The award supports investigator-initiated biomedical research focused on understanding the mechanisms of resilience to cytokinopathy flares in autoinflammatory diseases. The research addresses...
- Federal Project Grant Award Summary Yale University received a $778,828 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 6, 2026, with a completion date of March 31, 2031. This award supports investigator-initiated research examining novel loss-of-function gene variants in ZFYVE21 and their role in dysregulated innate immunity. The research deliverables include...
- Federal Project Grant Award Summary Yale University received a $2,685,326 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded July 7, 2025, with a completion date of June 30, 2029. The award supports biomedical research investigating the regulation of neutrophil plasticity, heterogeneity, and functional ambivalency by Wnt5 proteins in the context of colitis. The research focuses on...
- Federal Grant Award Summary Yale University received a $3.13 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 25, 2025, with a completion date of June 30, 2029. The grant funds investigator-initiated biomedical research focused on elucidating the mechanisms of lymphoid-specific beta-catenin protein degradation in B-lymphoid cells. The research will characterize how B-cells...
- Federal Grant Award Summary Yale University received a $735,631 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 1, 2026, with completion targeted for March 31, 2031. The research focuses on investigating the origin and functional properties of CX3CR1+ neutrophils, a novel neutrophil population with distinct biological characteristics compared to canonical neutrophils....
- Federal Grant Award Summary Yale University received a $373,090 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 25, 2025, with a completion date of July 31, 2026. The award supports development of Modular Degraders of Extracellular Proteins (MODES), a novel therapeutic approach designed to remove pathogenic extracellular proteins from circulation. The research program...
- Federal Grant Award Summary Columbia University's Health Sciences Division received a $821,018 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective May 1, 2026, with a completion date of February 28, 2031. The award funds basic biomedical research investigating the immunological mechanisms underlying celiac disease (CD), specifically examining...
- Federal Grant Award Summary Yale University received a $4.9 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 14, 2025, with a completion date of June 30, 2029. The grant supports biomedical research investigating the mechanistic pathways by which gut microbiota and white adipose tissue control the CD4 T-cell compartment and facilitate T-cell migration from the...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $661,009 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2031. This award funds a comprehensive genetic and immunological investigation of ABCF1 (ATP-Binding Cassette Sub-Family F Member 1) in celiac disease and autoimmunity. The research...
- Federal Project Grant Award Summary Yale University received a $3.26 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2029. The award funds research to elucidate molecular mechanisms of Mycobacterium tuberculosis (MTB) cell envelope assembly, with the goal of identifying drug synergy opportunities to enhance antibiotic efficacy. The...
Yale University received a $2.33 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 17, 2026, with completion targeted for April 30, 2031. The award funds laboratory-based research to advance understanding of celiac disease (CD) pathogenesis and develop clinically useful biomarkers for disease activity assessment. The project applies advanced technologies—including pan-expansion microscopy, immunopeptidomics, spatial transcriptomics, and automated cyclic immunofluorescence—to analyze duodenal mucosal biopsies and organ cultures from celiac disease and control subjects. This research directly addresses knowledge gaps in T cell immunopathology underlying celiac disease, a common autoimmune disorder triggered by dietary gluten in genetically predisposed individuals. The award supports collaborative, multidisciplinary research conducted by accomplished researchers at Yale School of Medicine in New Haven, Connecticut, with critical input from expert clinician-scientists at four collaborating centers: Yale, Children's Hospital Colorado, Massachusetts General Hospital, and Vanderbilt University Medical Center. The integrated research approach is designed to reveal details regarding cytotoxic T lymphocyte populations that infiltrate and damage the epithelial lining of small intestinal villi, with findings intended to contribute to both therapeutic development and the creation of measurable disease activity indicators for which no current effective measures exist.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.3m | 6/19/26 |