Project Grant K99NS144632
- This federal Project Grant award of $501,125.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to determine the mechanisms of dopamine transmission in the brain and how it regulates motor function and learning. The research aims to understand how different dopamine signals mediate transmission and impact aspects of motor activity and learning,...
- This federal Project Grant award of $761,591 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) is funding research to characterize the firing patterns of spinal neurons during motor behaviors in mice. The goal is to better understand how the spinal cord processes motor commands for limb movements. The award to the Salk Institute for Biological Studies in La Jolla, CA...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to identify the electrophysiological characteristics of spinal motor neurons during the recovery stages following a spinal cord injury (SCI) in mouse models. The $470,293 award to the Research Foundation for the State University of New York (RF SUNY) at Binghamton will employ soft,...
- This federal Project Grant award of $340,822 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research by Drexel University to investigate the role of inhibitory interneurons in the dorsal horn of the spinal cord as a potential target for improving locomotor function following spinal cord injury. The research aims to better understand...
- This Project Grant award of $469,898 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), which administers the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award to Yale University supports research to define the capacity and necessity of intact and lesioned supraspinal raphespinal tract terminals in supporting rehabilitation-induced functional recovery after spinal cord injury. The proposed...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $566,382 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Temple University. The 5-year grant, effective August 15, 2025, will support research to investigate novel therapeutic strategies for restoring sensory connections in the spinal cord after dorsal root injuries. The research aims to determine if specific subtypes of sensory axons prematurely...
- The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $184,837 Project Grant to The Ohio State University on April 25, 2025. The grant supports research on promoting spinal cord repair using a polymer-based drug delivery system. The project aims to investigate the use of targeted intraspinal delivery of gabapentinoids, a class of drugs that can promote axon...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research at the University of Louisville to investigate the role of propriospinal neurons in spinal cord injury recovery. The $462,296 award, with a period of performance from June 3, 2025 to May 31, 2030, will enable the researchers to use advanced tools like virus-based...
- This federal Project Grant award of $572,715.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to investigate the role of spinal dopamine receptor mechanisms in regulating the micturition (urination) reflex after spinal cord injury. Key objectives include determining if spinal D1-D2 receptor heteromers regulate...
- This $424,875.00 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund a comprehensive study of gene transcription patterns in diverse classes of neurons that connect the brain to the spinal cord after spinal cord injury in a mouse model. The research team at Marquette University will use single-cell sequencing technologies to profile...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $123,588 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Rutgers, The State University in New Jersey. This 2-year grant, awarded on September 1, 2025, will support research to explore the relationship between altered motor behavior and dopamine transients in the dorsolateral striatum following spinal cord injury. The research aims to establish baseline dopamine dynamics during motor recovery, define dopamine transients in specific post-injury behaviors, evaluate the effects of sensory-based exercise, and assess real-time modulation of dopamine in motor action selection and sequencing. This project combines advanced techniques such as photometry in awake mice, AI-driven behavioral characterization, mouse genetics, and optogenetics to investigate the role of striatal dopamine signaling in motor recovery after spinal cord injury.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $123.6k | 7/31/25 |