Project Grant R01NS145451
- This federal Project Grant award of $340,822 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research by Drexel University to investigate the role of inhibitory interneurons in the dorsal horn of the spinal cord as a potential target for improving locomotor function following spinal cord injury. The research aims to better understand...
- The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $184,837 Project Grant to The Ohio State University on April 25, 2025. The grant supports research on promoting spinal cord repair using a polymer-based drug delivery system. The project aims to investigate the use of targeted intraspinal delivery of gabapentinoids, a class of drugs that can promote axon...
- This federal Project Grant award for $102,876.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The funding supports research by Temple University-Of The Commonwealth System Of Higher Education to investigate the role of protein palmitoylation in axon degeneration, a key mechanism underlying diverse neurological conditions. The research aims to better...
- This Project Grant award of $100,272.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand how axon guidance is regulated in the mature nervous system. The research aims to identify molecular and cellular mechanisms that regulate axon regeneration and guidance, with a focus on using the Caenorhabditis elegans model system to study an...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $427,625 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Washington. The project aims to explore whether electrical stimulation can enhance the effectiveness of neural stem cell transplants in improving recovery from chronic spinal cord injury. The research will investigate if combining these two promising treatments can produce...
- This $540,322 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research at The Ohio State University on the role of 3D chromatin architecture in axonal regeneration following peripheral nerve injury. The objective is to investigate how the folding of the genome into topologically associating domains (TADs) and enhancer-promoter...
- This Project Grant award of $1,188,230 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to evaluate the cellular composition, activation state, and spatial niches involved in neuroma formation following severe peripheral nerve injuries. The primary goals are to validate preliminary data indicating that neutrophil extracellular traps (NETs) may be an...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund research at the University of Louisville to investigate the role of propriospinal neurons in spinal cord injury recovery. The $462,296 award, with a period of performance from June 3, 2025 to May 31, 2030, will enable the researchers to use advanced tools like virus-based...
- This Project Grant award of $567,037.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to characterize the synchrony between peripheral nerve post-injury activity and brain plasticity. The research will utilize an innovative optical imaging method to simultaneously monitor nerve regeneration and corresponding changes in the cerebral cortex in mice...
- This federal Project Grant award of $761,591 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) is funding research to characterize the firing patterns of spinal neurons during motor behaviors in mice. The goal is to better understand how the spinal cord processes motor commands for limb movements. The award to the Salk Institute for Biological Studies in La Jolla, CA...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $566,382 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Temple University. The 5-year grant, effective August 15, 2025, will support research to investigate novel therapeutic strategies for restoring sensory connections in the spinal cord after dorsal root injuries. The research aims to determine if specific subtypes of sensory axons prematurely terminate regeneration through synaptic arrest with oligodendrocyte precursor cells, as well as evaluate if viral activation of specific axon subtypes or transient oligodendrocyte ablation can overcome this arrest to enable modality-specific functional regeneration.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $566.4k | 8/1/25 |