This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $238,500 to the University of Pittsburgh to evaluate the use of epidural spinal cord stimulation (SCS) to regain bladder function in cats with chronic spinal cord injury (SCI). The key objectives are to: Determine if both micturition (urination) and continence can be evoked...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $469,898.00 to Yale University to conduct research on mechanisms that support raphespinal tract plasticity and regeneration after spinal cord injury. The research aims to use anatomy, spatial transcriptomics, and intersectional in vivo chemogenetics to define the capacity and...
This federal Project Grant award, totaling $481,049.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The project, titled "Substantia Nigra Circuits in Instrumental Action," aims to characterize how the substantia nigra pars reticulata (SNR) regulates divergent nigrostriatal dopamine pathways and determine the roles of specific...
This federal Project Grant award of $173,140 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to investigate the role of neural activity in the degeneration of midbrain dopamine neurons, which is a key feature of Parkinson's disease. The research project, which runs from September 30, 2024 to June 30, 2027, will utilize novel mouse models to...
This $625,060 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will fund research to elucidate the roles of distinct spinal cord cell types in mediating interstitial cystitis (IC)/bladder pain syndrome (BPS). The research, conducted by The Washington University in St. Louis, will use chemogenetics and optogenetics approaches to determine the...
This $424,875.00 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund a comprehensive study of gene transcription patterns in diverse classes of neurons that connect the brain to the spinal cord after spinal cord injury in a mouse model. The research team at Marquette University will use single-cell sequencing technologies to profile...
This federal Project Grant award, totaling $1,612,516.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant, awarded on August 1, 2024, supports research at the University of Illinois focused on investigating the role of nicotinic acetylcholine receptors in neuropathic pain. The project aims to advance scientific understanding of the neural...
The federal Project Grant award of $1,793,411 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab), a non-profit hospital and research institute. The funding will support a research project titled "SAFETY AND EFFICACY OF AMPAKINES FOR IMPROVEMENT OF BLADDER FUNCTION IN INDIVIDUALS WITH SCI" over the period of July 1, 2024 to June 30,...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $411,941 to Drexel University to conduct research on identifying novel trunk reflex pathways and how they differ after neonatal versus adult spinal cord injury in animal models. The key objectives are to test the hypothesis that the newly discovered contralateral monosynaptic trunk...
This Project Grant award of $597,999.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will fund research focused on understanding the neuronal populations and central sensitization mechanisms that underlie mechanical allodynia, a condition where normally innocuous touch or movement becomes painful after an injury. The research...