This Project Grant award, titled "Promoting Spinal Cord Repair Using a Polymer-Based Drug Delivery System", is funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $184,837 award aims to develop a novel polymer-based drug delivery system for localized intraspinal administration of gabapentinoid drugs to promote axon regeneration and functional recovery following spinal cord injury (SCI) in adult mice. Key objectives include optimizing the physicochemical properties of the drug-loaded microspheres, and evaluating their efficacy in enhancing axon regeneration and SCI repair in in vitro and in vivo models. The award was granted on April 25, 2025 to The Ohio State University, with a projected completion date of March 31, 2027. This research builds upon the university's expertise in biomedical sciences, drug delivery systems, and spinal cord injury therapeutics to advance potential treatment strategies for traumatic SCI.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $184.8k | 4/25/25 |