Project Grant K99GM164664
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $462,119 Project Grant on September 8, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and deploy TRACK-IT (Transposon Accelerated Chromatin Kinetic Imaging Technology), a next-generation live-imaging platform for studying three-dimensional genome motion and dynamics. The research aims to advance understanding of how genome organization...
- Federal Project Grant Award Summary The Leland Stanford Junior University received a $157,388 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on August 9, 2026, with a completion date of August 8, 2027. The research project, titled "Rewiring Nucleosome Engagement Through Chemically Induced Proximity," investigates the application of chemically induced proximity (CIP)...
- Federal Grant Award Summary The Leland Stanford Junior University received a $616,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded on March 12, 2026, with a completion date of February 29, 2028. The award supports the development of next-generation proximity labeling (PL) enzymes to advance spatial proteomics research in living cells. The project focuses on engineering and...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a Project Grant of $225,144 under the Biomedical Research and Research Training program (CFDA 93.859) on August 9, 2026, with a completion date of February 15, 2029. This award supports the development of self-assembling pyrrole-imidazole polyamides (PY-IM PA) using proximity-induced bioorthogonal chemistry for the treatment of Friedreich's ataxia and prostate...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a Project Grant totaling $2,117,247 under the Biomedical Research and Research Training program (CFDA 93.859) on September 11, 2025, with a completion date of August 31, 2029. This award supports fundamental research investigating the genetic basis of complex traits across multiple model organisms and human populations. The research focuses on developing and applying experimental...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $423,500 Project Grant to The Leland Stanford Junior University on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). This award funds research focused on understanding the regulatory mechanisms that control mitochondrial transport and quality control in neurons through the completion date of January 31, 2031. The research addresses how mitochondria move...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $385,000 Project Grant effective March 1, 2026, through December 31, 2030, under the Biomedical Research and Research Training program (CFDA 93.859). This five-year research initiative will advance fundamental understanding of three-dimensional (3D) genome folding in single cells by developing and implementing systematic large-scale genetic and chemical perturbation screening...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded a $192,500 Project Grant to The Leland Stanford Junior University beginning September 1, 2025, and concluding August 31, 2027, under the Biomedical Research and Research Training program (CFDA 93.859). This award supports the development of SPLASH (Split Protein Ligation Activated by Steroid Hormone), a novel drug-regulated protein activation platform designed to enable rapid induction of...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Stanford University a $125,000 Project Grant on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support a two-year research initiative concluding April 30, 2028. The award funds the development of novel membrane-centric proximity labeling technologies designed to systematically map lipid-protein and protein-protein interaction networks in living...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a Project Grant of $423,500 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct research on the molecular mechanisms governing membrane protein complex assembly at the human endoplasmic reticulum. The project, awarded March 6, 2026 with a completion date of February 28, 2031, will employ an integrated approach combining...
The National Institute of General Medical Sciences (NIGMS) awarded The Leland Stanford Junior University a $125,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to support fundamental research on the molecular organization and function of oocyte spindles. Awarded on May 1, 2026, with a completion date of April 30, 2028, this two-year research initiative addresses critical gaps in understanding how oocytes assemble functional spindles without centrosomes—a process termed acentrosomal meiosis. The research responds to the significant public health challenge that 10-25% of human embryos contain chromosomal abnormalities (aneuploidy), with oocyte aneuploidy rates reaching 25% and increasing dramatically after age 35, thereby contributing to age-related infertility and birth defects. The project investigates the genetic and molecular mechanisms governing acentrosomal spindle assembly and the role of tubulin isotype composition in chromosome segregation fidelity. Utilizing Caenorhabditis elegans as a model organism, researchers employ innovative tools including GFP-tagged microtubule-severing enzyme katanin and tubulin variants to dissect spindle assembly dynamics, microtubule structural integrity, and anaphase segregation velocity. This basic research is anticipated to advance fundamental understanding of oocyte reproduction and establish foundational knowledge for future diagnostic and therapeutic interventions targeting age-related fertility decline and chromosomal abnormalities.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $125.0k | 4/28/26 |