Project Grant K99GM160780
- Federal Project Grant Award Summary The University of California, San Francisco received a $410,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025 through June 30, 2030. The award supports development of novel computational and analytical approaches to reconstruct heterogeneous infectious disease transmission dynamics from pathogen genomic sequence data. The...
- Federal Project Grant Award Summary The University of California, San Francisco received a $501,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 5, 2025, with completion targeted for May 31, 2030. The grant funds fundamental research focused on bridging the gap between predicted and actual protein structures in structural biology, with particular emphasis on understanding...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant totaling $395,692 to the University of California, San Diego on July 17, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The five-year award, with a completion date of June 30, 2030, supports research to enhance bacteriophage function through coevolution and synthetic biology approaches to address antimicrobial resistance (AMR). The project will...
- Federal Grant Award Summary The University of California, San Francisco received a $445,049 Project Grant award from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026, through March 31, 2031. This research initiative develops innovative lipid nanoparticle (LNP) formulations designed to achieve cell-type-specific delivery of programmable RNA therapeutics. The project integrates bio-inspired...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $492,000 to The Regents of the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 1, 2025, for a five-year project period concluding July 31, 2030. The award funds biochemical and structural characterization research of the elongasome and divisome protein complexes in Mycobacterium tuberculosis (MTB) and the...
- Federal Grant Award Summary The University of California, San Francisco received a $562,484 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective May 1, 2026 through April 30, 2031. This five-year award supports the development of next-generation visualization and analysis software tools designed to enable scientific discovery in biomedical research through integrated analysis of multiscale...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded $576,104 to The Regents of the University of California, San Francisco under the Biomedical Research and Research Training program (CFDA 93.859) on August 15, 2025, for a project titled "Molecular Basis for Transmembrane Conduction & Signaling." This five-year project, scheduled for completion by July 31, 2030, supports fundamental research to determine the atomic-level mechanisms...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded UC Berkeley $441,375 under the Biomedical Research and Research Training program (CFDA 93.859) for a five-year project (April 1, 2026 – March 31, 2031) investigating the cellular and developmental mechanisms underlying animal responses to intracellular beneficial microbes. The research utilizes the sea anemone Aiptasia as a genetically tractable model organism to study the endosymbiotic...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Regents of the University of California, San Francisco $158,240 under the Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on cell-cell contact formation mechanisms. The project, awarded on March 5, 2026, and scheduled for completion by November 30, 2027, investigates how E-cadherin clusters and the actomyosin cortex mechanically interact to...
- Federal Project Grant Award Summary San Francisco State University received a $465,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through May 31, 2029. The award supports fundamental biomedical research investigating the necessity of RNA degradosome assembly in Sinorhizobium meliloti for effective symbiosis. Specifically, the project will elucidate...
The National Institute of General Medical Sciences (NIGMS) awarded $123,147 to The Regents of the University of California, San Francisco under the Biomedical Research and Research Training program (CFDA 93.859) on May 13, 2026, with completion anticipated by April 30, 2028. This project grant funds fundamental biomedical research investigating the infection mechanisms of jumbo bacteriophages (large DNA viruses with genomes exceeding 200 kilobases), specifically the FKZ phage family and their interactions with antibiotic-resistant pathogens such as Pseudomonas aeruginosa. The research addresses the critical public health challenge of antibiotic resistance by exploring how these naturally occurring phages evade bacterial immune defenses—knowledge essential for developing phage-based therapeutics as alternative antimicrobials. The deliverables encompass advanced scientific investigation into the biogenesis and function of phage-derived cellular structures, including the early phage infection vesicle (EPIV) and phage nucleus, using cutting-edge analytical techniques including cryo-electron tomography (cryo-ET), mass spectrometry, and genetic analysis. The research will characterize a novel messenger RNA export mechanism within the EPIV compartment, examine pseudolysogeny pathways, and generate foundational knowledge applicable to phage-based treatment strategies. The project is conducted at UCSF's San Francisco facility, leveraging the institution's established capabilities in biomedical and infectious disease research.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $123.1k | 5/13/26 |