Project Grant K99AI190315
- Federal Grant Award Summary Rockefeller University received a $862,748 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 23, 2026, with a completion date of January 31, 2031. The research initiative, titled "Elucidating the Host and Viral Determinants of Treatment Response in Chronic Hepatitis B," addresses a significant public health challenge, as...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Rockefeller University a Project Grant of $798,670 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 1, 2026, through May 31, 2031. This award supports investigator-initiated biomedical research focused on developing novel antibiotics through bioinformatics-guided synthesis methods targeting previously inaccessible microbial biosynthetic pathways....
- Federal Project Grant Award Summary Rockefeller University received a $667,659 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 1, 2026, through May 31, 2031. The award supports functional genomic research aimed at identifying condition-specific vulnerabilities in Mycobacterium abscessus (MABS), a pathogen causing chronic lung infections in patients with cystic fibrosis...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,741 to the Scripps Research Institute under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning April 1, 2026, with a completion date of March 31, 2031. This Project Grant funds the development of a long-acting injectable (LAI) therapy for hepatitis B virus (HBV) treatment in individuals co-infected with human immunodeficiency virus (HIV). The research addresses a...
- Federal Project Grant Award Summary Rockefeller University received a $466,125 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 1, 2025, with completion scheduled for June 30, 2027. The funded research focuses on elucidating the genetic basis of incomplete penetrance in isolated congenital asplenia (ICA) caused by RPSA haploinsufficiency. The project delivers investigative...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $101,396.00 to Icahn School of Medicine at Mount Sinai under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective March 10, 2026, with completion anticipated by September 14, 2029. The award supports investigator-initiated biomedical research examining how hepatocytes and skeletal myocytes influence adaptive immune responses to messenger RNA (mRNA)...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $659,663 to the Beckman Research Institute of the City of Hope under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 1, 2025, for a five-year project period concluding July 31, 2030. The grant supports fundamental research investigating the role of RNA modification in the development and function of invariant natural killer T (iNKT) cells, specialized...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $195,750 to the Baruch S. Blumberg Institute under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 10, 2026, with a completion date of January 31, 2028. The research initiative focuses on developing and validating a novel RNA sensing and editing-dependent reporter system to identify cellular functions involved in Hepatitis B Virus (HBV)...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Research Foundation for the State University of New York a Project Grant of $240,150 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 24, 2025, with completion scheduled for June 30, 2027. This research initiative investigates the mechanisms by which the Large Tumor-Antigen (LT) protein from polyomaviruses cooperates with the ETS1 proto-oncogene...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Weill Medical College of Cornell University a Project Grant totaling $806,208.00 (Award Date: September 4, 2025; Completion Date: August 31, 2030) under the Allergy and Infectious Diseases Research program (CFDA 93.855). This project, titled "Spatial Omics to Understanding HBV Control in People with HIV Coinfection," advances research into hepatitis B virus (HBV) treatment...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded Rockefeller University a Project Grant of $195,523 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 3, 2026, with completion targeted for May 31, 2028. This K99 Pathway to Independence award supports research investigating the mechanisms by which hepatitis B virus (HBV) episomal DNA transcription is silenced and promoted. The grant funds a mentored research phase focused on characterizing how covalently closed circular DNA (cccDNA) transcription is regulated through host proteins and their interactions with HBV's regulatory X protein (HBX), with particular emphasis on understanding the roles of non-SMC element 3 (NSE3) and mitochondrial topoisomerase 1 (TOP1MT) as host factors disrupted by HBX. Under this award, the principal investigator will develop technical capabilities and receive training in advanced research methodologies including deep mutational scanning (DMS) to identify the genetic basis for HBX-promoted viral RNA expression and CRISPR interference (CRISPRi) techniques to discover previously unidentified host factors involved in episomal circular DNA transcription. The comprehensive career development plan additionally incorporates professional training in project management, mentorship, and grant writing to support the investigator's transition to research independence. Research will be conducted at Rockefeller University's facility in New York.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $195.5k | 6/3/26 |