Project Grant R01AI195435
- The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a $781,367 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Weill Medical College of Cornell University. The grant, awarded on January 25, 2024, will support research to define and maximize the impact of CD8+ T-cell selection on the landscape of HIV integration sites. The goal is to optimize strategies for eradicating the persistent reservoir of HIV-infected cells and achieve...
- This $510,306 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to advance the understanding of virus-host interactions for developing a cure against chronic hepatitis B virus (HBV) infections. The primary goal is to investigate the mechanisms by which interferon-alpha treatment can lead to a functional cure for HBV, as well as explore the impact of HBV...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $5,504,270 Cooperative Agreement to The Johns Hopkins University on September 26, 2025 under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The award will establish a multinational cohort of people with HIV and chronic hepatitis B (PWHHB) to apply novel technologies and advance a hepatitis B virus (HBV) functional cure. The project aims to characterize mechanisms of intrahepatic HBV...
- This Project Grant award of $149,389, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to characterize the clonal landscape of the HIV reservoir in CD4 cells. The awardee, Weill Medical College of Cornell University, will isolate and culture pure CD4 HIV reservoir clonal populations to phenotypically, genotypically, and functionally analyze them. This includes...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,275,484 Cooperative Agreement to Weill Medical College of Cornell University on August 12, 2025 under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The goal of this project is to identify an optimal prime-boost immunization strategy to guide antibody maturation towards broad neutralization of HIV in early life. The project aims to: 1) Compare sequential versus simultaneous...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $238,972 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Research Foundation for the State University of New York, doing business as Sponsored Projects Services, to study the role of the cellular protein EHD4 in restricting HIV-1 infection. The research aims to determine the mechanism by which EHD4 decreases the infectivity of HIV-1 particles by impacting the incorporation of...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $147,486 to Weill Medical College of Cornell University to conduct research on identifying metabolic profiles in HIV-infected CD4+ T-cells that are resistant to cytotoxic T-lymphocyte (CTL) elimination. The goal is to better understand mechanisms of HIV reservoir persistence during antiretroviral therapy, which is a key barrier to curing HIV...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $859,992 Project Grant to Yale University for the "Molecular Investigations of HIV-1 Maturation Pathways and Inhibitor Actions in situ" research project. The grant, funded under NIAID's Allergy and Infectious Diseases Research Program (CFDA 93.855), aims to use advanced in-situ cryo-electron microscopy and tomography techniques to visualize the structural transitions of the HIV-1 virus during the maturation...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $776,341 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Illinois on September 16, 2025. The purpose of this grant is to develop a microfluidic cartridge, molecular biology method, biosensor, and detection instrument that can simultaneously detect HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) viral loads from a minimal 100 μL whole blood sample. This...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3,568,644 Cooperative Agreement under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Wistar Institute of Anatomy and Biology, a non-profit biomedical research institute. The award aims to develop an individualized HIV cure strategy that combines enhanced neutralizing antibody responses, antiviral adaptive NK cells, and engineered cell-mediated effector strategies. The goal is to characterize...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $806,208 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to Weill Medical College of Cornell University. The project, titled "Spatial Omics to Understanding HBV Control in People with HIV Coinfection," will leverage cutting-edge spatial proteomic and transcriptomic technologies to analyze the impact of HIV-related immune suppression and restoration on the hepatitis B virus (HBV) liver reservoir and liver microenvironment in a cohort of people with HBV/HIV coinfection in Zambia. The goal is to advance the development of HBV cure strategies, particularly for individuals with HBV/HIV coinfection who face increased liver-related mortality. The award period runs from September 4, 2025 to August 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $806.2k | 9/4/25 |