Project Grant K24DA063801
- This $825,383 federal Project Grant award was provided by the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), to the University of Massachusetts Medical School (UMMS) located in Worcester, MA. The grant supports research to investigate the relationship between disruptions in molecular rhythms in specific cell types of the striatum and opioid use disorder (OUD) using human postmortem brain samples and mouse models. The project aims to...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the CFDA program "Drug Use and Addiction Research Programs" (93.279), will support research to uncover the neurophysiological signatures within the addiction circuitry related to acute opioid use. The $159,711 award, effective January 1, 2025 through December 31, 2029, will leverage a unique ability to directly record local field potentials from awake humans with implanted brain electrodes. This will...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Abuse and Addiction Research Programs (CFDA 93.279) provides $318,257 to Cari Health, Inc. to develop a therapeutic monitoring system (TMS) for remote medication compliance tracking of methadone treatment for opioid use disorder (OUD). The key products and services to be delivered include: 1) Integrating an electrochemical sensor, microneedle array, and data pipeline into a prototype wearable...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a study to characterize treatment utilization and identify predictors of treatment engagement during the critical community re-entry period for adults with opioid use disorder (OUD) who have completed residential OUD treatment. The $147,486 award, with a performance period from December 20, 2024 to August 31, 2026, will leverage innovative...
- This $1,360,092 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a study to assess social functioning among individuals with opioid use disorder (OUD) and their concerned significant others (CSOs) during OUD treatment. The study will use ecological momentary assessment and a smartwatch-based application to collect both subjective self-reports and objective measurements of social behaviors, social...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), has awarded a $306,872 Project Grant to Biomotivate LLC to develop and evaluate the PEACE Platform, a novel solution that leverages personalized audiovisual content and machine learning algorithms to help individuals with opioid use disorders (OUDs) build their capacity to manage negative emotions and stressors. The research design involves integrating generative AI, predictive...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA), part of the U.S. Department of Health and Human Services, is funded through the Drug Use and Addiction Research Programs (CFDA 93.279). The $454,251 award will support the development of a new approach for long-term monitoring of opioid-induced changes in neural population activity and opioid receptor gene expression in mice exposed to fentanyl. Specifically, the project aims to create "erasable"...
- This federal Project Grant award, titled "Dynamic Treatment Regimes for Personalized Opioid Use Disorder Care," was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $199,800 award supports the research efforts of Dr. Jason Brian Gibbons, an Assistant Professor at the University of Colorado Anschutz Medical Campus, over a 5-year period from August 2025 to July 2030. The overarching objective of the project is...
- This $147,486 federal Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) will support a mixed-methods study examining the predictors and outcomes of methadone and buprenorphine receipt during incarceration. The study will analyze a longitudinal database on health service use and outcomes among 4,558 incarcerated individuals who received these medications from 2016-2023 at a unified jail and prison system in the Northeast....
- This Project Grant award of $398,137 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is for developing high-precision epigenetic therapeutics to address the growing opioid use disorder (OUD) epidemic in the United States. The award will enable Boston Interactome LLC to apply a novel approach targeting protein-protein interactions of the neuronal G9A complex, a key regulator of DFosB expression under chronic opioid exposure....
This federal Project Grant award of $144,252 from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) will fund a research program led by Dr. Carreiro at the University of Massachusetts Medical School (UMMS). The key objectives are to: Develop a novel wearable sensing system called "MINDER" to continuously monitor physiological parameters and use machine learning to accurately identify adherence to buprenorphine treatment for opioid use disorder. This includes curating a high-quality dataset of physiological data from individuals undergoing buprenorphine induction and building the machine learning algorithms. Model wearable sensor-based digital biomarkers of opioid craving in patients receiving medications for opioid use disorder, and develop associated digital phenotypes. The award period runs from September 1, 2025 to August 31, 2030, and the research aims to advance personalized solutions to the opioid use disorder epidemic by leveraging Dr. Carreiro's expertise in precision medicine and mentoring a diverse group of scientists in this domain.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/17/25 | ||
| Not listed | $144.3k | 8/25/25 |