Project Grant K23NS136771
- This federal Project Grant award of $414,305 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund research to identify key molecules and pathways underlying the process of epileptogenesis, with the goal of developing therapies to modify disease progression. The research leverages a novel algorithm called MAGIC combined with a large...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $222,160 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of California, San Diego (UCSD). The grant will support Dr. Alena Stasenko's research to develop risk and resilience models of cognitive aging in epilepsy and novel, tech-based interventions to improve brain health. The project aims to leverage digital assessment to determine the...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA 93.853 "Extramural Research Programs in the Neurosciences and Neurological Disorders", provides $230,904 to Boston Children's Hospital from January 1, 2025 to December 31, 2029. The award will support research to identify novel genetic causes of infantile epilepsies and evaluate the impact of genetic diagnosis on patient outcomes and families. Key objectives include applying...
- This federal Project Grant award of $238,356 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to study the role of the amygdala-nucleus reticularis thalami (NRT) pathway in modulating thalamocortical circuits and cortical activity, and its potential impact on seizures and neuropsychiatric comorbidities in people with epilepsy. The research, led by the...
- This $1,309,206 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate spatial recognition memory processes in patients with epilepsy. The goal is to develop improved cognitive assessments and treatments for the memory deficits commonly experienced by epilepsy patients, which are not well captured by current neuropsychological...
- This Project Grant award of $743,776 from the National Institute of Neurological Disorders and Stroke (NINDS, CFDA 93.853) supports research to determine whether and when ablating mutant cells that cause epilepsy can reverse the disease in mouse models of mTOR pathway disorders. The research aims to advance the development of AAV-mediated gene therapy approaches to treat intractable epilepsy caused by mTOR pathway mutations. This work builds upon almost two decades of the recipient...
- This Project Grant award of $555,499 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) is funding research to develop novel, non-invasive behavioral biomarkers for predicting seizures and mortality in mouse models of epilepsy. The principal investigators at Stanford University, in collaboration with researchers at Harvard Medical School, will use artificial...
- This federal Project Grant award of $225,599, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research on the contributions of sex chromosomes versus gonadal hormones in shaping sex differences in epilepsy. The University of Illinois, the awardee, will utilize in vivo video-electroencephalography, RNA sequencing, and immunostaining to determine...
- This federal Project Grant award, ID R01NS137650, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $580,070 award, effective December 1, 2024 through November 30, 2029, will support research at Stanford University to study the role of the human thalamus in the propagation of temporal lobe seizures and memory formation. The key products and...
- This $579,294 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to understand the cell type-specific epigenetic mechanisms, particularly involving microRNAs, that regulate brain function and contribute to neurological disorders like epilepsy. The research aims to reveal the specific cell types and target mRNAs...
This Project Grant award of $228,420.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to investigate the impact of genetic variants and pathways in women with epilepsy (WWE) and their children on the children's long-term cognitive status after fetal exposure to anti-seizure medications. The research project seeks to create a better predictive model of neurocognitive outcomes in children of WWE by combining clinical/external factors and genetic/intrinsic biomarkers. The award has an ultimate completion date of July 31, 2030 and is being conducted by the Leland Stanford Junior University, a leading private research institution.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $228.4k | 7/30/25 |