Project Grant K23NS131522
- This federal Project Grant award of $414,305 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund research to identify key molecules and pathways underlying the process of epileptogenesis, with the goal of developing therapies to modify disease progression. The research leverages a novel algorithm called MAGIC combined with a large...
- This federal Project Grant award of $431,676 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) is funding research to investigate the role of the glucocorticoid receptor (GR) and its interaction with the cytochrome P450 (CYP) and P-glycoprotein (PGP) pathways in regulating anti-seizure medication bioavailability across the blood-brain barrier in drug-resistant epilepsy with...
- This federal Project Grant award of $390,000.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the role of dysregulated eIF4E-mediated translational control in the pathogenesis of Focal Cortical Dysplasia Type II (FCDII), a neurodevelopmental disorder that causes focal cortical malformations and drug-resistant epilepsy. The...
- This $579,294 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to understand the cell type-specific epigenetic mechanisms, particularly involving microRNAs, that regulate brain function and contribute to neurological disorders like epilepsy. The research aims to reveal the specific cell types and target mRNAs...
- This $1,309,206 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate spatial recognition memory processes in patients with epilepsy. The goal is to develop improved cognitive assessments and treatments for the memory deficits commonly experienced by epilepsy patients, which are not well captured by current neuropsychological...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $438,836 to The Trustees of the Stevens Institute of Technology under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research to develop a unified paradigm using simultaneous multimodal measurement of scalp EEG and intracranial EEG (iEEG) signals to estimate the electrophysiological networks of the whole brain....
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $426,250 Project Grant under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. This 2-year grant will fund research using cutting-edge voltage imaging to examine how interactions between specific neuronal circuit elements in the hippocampus relate to the development of temporal lobe...
- This Project Grant award of $743,776 from the National Institute of Neurological Disorders and Stroke (NINDS, CFDA 93.853) supports research to determine whether and when ablating mutant cells that cause epilepsy can reverse the disease in mouse models of mTOR pathway disorders. The research aims to advance the development of AAV-mediated gene therapy approaches to treat intractable epilepsy caused by mTOR pathway mutations. This work builds upon almost two decades of the recipient...
- This federal Project Grant award of $238,356 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to study the role of the amygdala-nucleus reticularis thalami (NRT) pathway in modulating thalamocortical circuits and cortical activity, and its potential impact on seizures and neuropsychiatric comorbidities in people with epilepsy. The research, led by the...
- This federal Project Grant award of $657,958 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is supporting research into the cellular and network mechanisms of epilepsy and neuromodulation. The research team from Trustees of Boston University will use cutting-edge cellular membrane voltage imaging, optogenetics, and local field potential recordings in cortical...
This $215,730 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding research by the Children's Research Institute to determine network signatures of pharmacoresistance in focal cortical dysplasia-related epilepsy. The goal is to identify quantitative local, regional and remote network connectivity alterations and network hub reorganizations associated with pharmacoresistance in this common cause of surgically-remediable, pharmacoresistant epilepsy in children. This 5-year research project aims to inform earlier identification and utilization of epilepsy surgery to improve outcomes for affected children, as guided by recent NINDS epilepsy research benchmarks.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $215.7k | 7/30/25 |