Project Grant K23MH141272
- The National Institute of Mental Health awarded $186,839 to the Research Institute At Nationwide Children's Hospital on August 15, 2026, under the Mental Health Research Grants program (CFDA 93.242) for a K23 career development grant supporting research into the static and dynamic neurocircuitry associated with fluctuations in non-suicidal self-injury. The award funds a longitudinal training study that will examine temporal variability in non-suicidal self-injury urges and behaviors by...
- The National Institute of Mental Health awarded the University of Pittsburgh $378,984 on March 13, 2026, under the Mental Health Research Grants program (CFDA 93.242) to test an integrative neurobiological model linking peripheral inflammatory markers to dysfunction in reward-related corticostriatal circuitry and adolescent suicidal ideation. The project, designated K23MH138759, will enroll 90 adolescents with unipolar depressive disorders enriched with those with a history of suicidal...
- The National Institute of Mental Health awarded the University of Pittsburgh $437,250 on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a longitudinal feasibility study examining the association between childhood gender nonconformity and early indicators of risk for suicidal behavior among children ages 7–10. The study collects data on psychosocial stressors, biological dysregulation in the hypothalamic-pituitary-adrenal axis and inflammatory pathways,...
- The National Institute of Mental Health awarded the University of Pittsburgh $381,463 on September 19, 2025, under the Mental Health Research Grants program (CFDA 93.242) to investigate neurocognitive responses to social threat and their links to social connectedness and suicidality in adolescent girls. The research employs multivariate electroencephalogram (EEG) decoding to assess neural representation of social threat information in working memory, ecological momentary assessment (EMA) to...
- The National Institute of Mental Health awarded the University of Pittsburgh $149,190 under the Mental Health Research Grants program (CFDA 93.242) on August 18, 2026 to examine pathways to suicidality through negative urgency, neural threat processing, and daily social rejection in young adults. The research utilizes data from an ongoing R01 grant including six months of ecological momentary assessment, a personalized peer social feedback fMRI task, and self-report questionnaires from 150 young...
- The National Institute of Mental Health awarded the University of Pittsburgh $458,433 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop, refine, and validate a developmentally-tailored and ecologically-valid adolescent emotional faces stimulus set and examine the extent to which adolescents' socioaffective processing of these stimuli predicts unique variance in symptoms of anxiety, depression, suicidal ideation, and lifetime history of suicidal...
- The National Institute of Mental Health awarded the University of Pittsburgh $751,430 on August 4, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a multi-omic atlas of dendritic spine morphometry across postnatal development in neurotypical and autism spectrum disorder subjects. The research interrogates trajectories of synaptic protein network features—protein expression, synaptosome levels, and phosphorylation—in the prefrontal cortex and primary visual...
- The National Institute of Mental Health awarded the University of Massachusetts Medical School $125,169 on July 30, 2026, under the Mental Health Research Grants program (CFDA 93.242, assistance type: Project Grant) to investigate brain metabolic dysfunction as a mechanism underlying autism spectrum disorder. The project uses non-invasive magnetic resonance spectroscopy to measure brain metabolites as markers of metabolic dysfunction in autistic adolescents relative to non-autistic peers,...
- The National Institute of Mental Health awarded the University of Pittsburgh $190,188 on June 3, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate the neural substrates of perseverative thought disengagement and reward learning in early adolescence, with emphasis on the role of puberty in internalizing symptom development among girls. The project characterizes neural correlates of two constructs impacted by developing cognitive-affective brain networks:...
- The National Institute of Mental Health awarded the University of Wisconsin–Madison $1.644 million on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a mechanistic analysis of the transition from nonsuicidal to suicidal self-injury in adolescents. The research project will employ a multi-method longitudinal approach to follow adolescents aged 13–17 over a two-year period through February 28, 2031. The study aims to identify which factors predict...
The National Institute of Mental Health awarded the University of Pittsburgh $190,185 on July 24, 2026, under the Mental Health Research Grants program (CFDA 93.242, K23 award mechanism) to conduct a longitudinal study examining behavioral and neural markers of compulsivity associated with nonsuicidal self-injury in autistic adults. The research integrates self-report, clinical interviews, functional MRI, and longitudinal data collection to characterize the relationship between compulsivity—defined as the tendency to engage in repetitive, often maladaptive thoughts or actions characterized by reduced goal-directed behavior—and nonsuicidal self-injury trajectories in autistic adults ages 18 to 45 years (N=90, with 50 percent oversampled for recent nonsuicidal self-injury within the past four months). The project addresses a critical gap in understanding nonsuicidal self-injury in autism, particularly given that at least half of autistic adults report a history of nonsuicidal self-injury and the condition carries a strong link to suicide attempts. Three research aims characterize associations between nonsuicidal self-injury and behavioral markers of compulsivity, neural markers of compulsivity, and identification of nonsuicidal self-injury trajectories in autistic adults. Findings are intended to support the development of targeted nonsuicidal self-injury prevention and intervention programs for autism. The award period runs from July 24, 2026, through June 30, 2031, with work performed in Pittsburgh, Pennsylvania. The K23 award mechanism supports up to five-year periods with no renewal option.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/5/26 | ||
| Not listed | $190.2k | 7/27/26 |