Project Grant K23HL177307
- This $292,500 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to identify novel microproteins associated with normal hematopoiesis and hematopoietic diseases. The project will leverage existing transcriptomic and translation data to produce a comprehensive catalog of microproteins expressed in different hematopoietic cell types. This inter-disciplinary research conducted by the Sanford Burnham Prebys Medical Discovery...
- This Project Grant award, valued at $242,250.00 and awarded by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), supports research to examine the relationship between atrial fibrillation, anticoagulation therapy, and retinal stroke. The research will utilize an instrumental variable approach to provide indirect evidence of the association between atrial fibrillation and retinal stroke, and how anticoagulation therapy may modify this relationship. The...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) is funding research to discover novel biomarkers and biological mechanisms underlying early-stage heart failure (HF). The $147,486 award to Duke University will support the development of an automated computational phenotype to identify early-stage HF, which will then be applied to large population cohorts. The research aims to leverage multi-omics data integration and...
- This federal Project Grant award of $1,119,410.00 was provided by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant supports a multi-disciplinary research initiative to investigate longitudinal changes in DNA methylation (LC-DNAM) and its relationship to cardiovascular disease (CVD) risk factors and outcomes across four large population-based cohort studies - ARIC, CARDIA, FHS, and MESA. The research aims to: 1)...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports a $771,485 research project titled "CAROTID-MAP CAROTID ATHEROSCLEROTIC RISK ASSESSMENT THROUGH IMAGING ANDPREDICTION". The project aims to develop reliable imaging-derived markers in carotid artery computed tomography angiography (CTA) scans to identify high-risk plaque features associated with cryptogenic stroke. The research...
- This Project Grant award, provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), funds a study to investigate the molecular mechanisms linking atrial cardiopathy to cardiovascular disease outcomes. The $1,657,473 award, granted on September 24, 2025, supports the use of proteomic and genomic methods in two diverse populations - individuals free of clinically recognized cardiovascular disease and patients with recent...
- The federal Project Grant award of $535,556.00 was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Alabama at Birmingham (UAB). The funding will support a research project to investigate the role of a novel histone modification, H3T32 O-GlcNAc, in endothelial cell dysfunction and atherosclerosis. The 5-year project aims to elucidate the epigenetic features of this histone modification under...
- This federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $766,667 to the Augusta University Research Institute, Inc. to investigate the role of neddylation, a protein modification process, in the development of cardiovascular diseases. The research aims to determine the significance of neddylation in maintaining vascular smooth muscle cell homeostasis and overall vascular health. Key research activities include...
- This $548,816 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research at the University of Illinois to investigate the role of the SEC16B protein in regulating lipid metabolism and transport in the liver. The project aims to define how SEC16B mediates the formation of lipid droplets and very low-density lipoprotein (VLDL) secretion, which are key processes involved in cholesterol and triglyceride homeostasis. This...
- This Project Grant award of $705,405 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to The Leland Stanford Junior University supports research focused on characterizing the role of adventitial fibroblasts in atherosclerosis. The research aims to identify new therapeutic targets and pathways related to this understudied cell population's influence on atherosclerotic plaque formation and calcification. The project will leverage single-cell genomics,...
This federal Project Grant award of $158,910.00, made by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports research by Dr. Qing Hao at Duke University to investigate the proteomic profile of intracranial atherosclerotic disease (ICAD) in order to identify novel biomarkers associated with ICAD occurrence and ICAD plaque activity. The research project aims to discover proteins and pathophysiological mechanisms specific to ICAD through proteomic analysis of intracranial arterial samples, and to examine proteins from peripheral blood samples to identify those associated with ICAD occurrence and active ICAD with acute stroke. The award has a performance period from August 15, 2025 to July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $158.9k | 8/18/25 |