Project Grant K23EY038334
- Federal Grant Award Summary Boston Children's Hospital received a $136,512 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) effective July 1, 2025, through June 30, 2027. The award supports research investigating how intrinsically photosensitive retinal ganglion cells (ipRGCs) transform light information in melanopsin pathways to regulate physiological and behavioral responses. The research employs advanced imaging techniques to measure...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded Oregon Health & Science University (OHSU) a $875,918 Project Grant effective August 1, 2025, through July 31, 2027, under the Vision Research program (CFDA 93.867). The project develops, evaluates, and validates large language models (LLMs) designed to automatically extract clinical data on amblyopia treatment, adherence, and outcomes from unstructured electronic health record (EHR) text. Amblyopia, a common pediatric...
- Federal Grant Award Summary The University of Chicago received a $929,806 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective from September 30, 2025, through September 29, 2027. The award supports research on synaptic development of the retinogeniculate pathway, examining how neural circuits form during childhood development and how both genetic and experiential factors influence this process. The primary research deliverables include...
- Project Grant Award Summary The National Eye Institute (Vision Research program, CFDA 93.867) awarded $855,250 to The Washington University in a Project Grant effective September 1, 2025, through August 31, 2027. This exploratory R21 research grant funds investigation into enhancing efferocytosis—the cellular clearance process of dying cells and debris—as a potential therapeutic intervention for oxygen-induced retinopathy (OIR), a leading cause of childhood blindness in the United States. The...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded $255,340 through the Vision Research program (CFDA 93.867) to The Regents of the University of California, San Francisco for a five-year project (May 1, 2026 – April 30, 2031) focused on understanding and regenerating retinal ganglion cells in the vertebrate retina. This research addresses glaucoma, which affects over four million Americans and represents the second leading cause of irreversible blindness globally. The...
- Federal Grant Award Summary The National Eye Institute (NEI), under its Vision Research program (CFDA 93.867), awarded Northwestern University a $1.62 million Project Grant on September 1, 2025, to develop computational models and diagnostic tools for improving glaucoma treatment outcomes. The three-year project, extending through August 31, 2028, focuses on modeling aqueous humor outflow based on a digital twin of the anterior eye imaged by robotic optical coherence tomography (OCT). The...
- Federal Project Grant Award Summary This $132,837 project grant, awarded on May 1, 2026, by the National Eye Institute under the Vision Research program (CFDA 93.867), funds research investigating SARM1 as a therapeutic target for two hereditary optic neuropathies: Autosomal Dominant Optic Atrophy (ADOA) and Leber Hereditary Optic Neuropathy (LHON). The research, conducted at Boston Children's Hospital in Massachusetts through April 30, 2028, aims to develop a novel therapeutic approach...
- Federal Grant Award Summary Akron Children's Hospital received a $786,350 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867), effective September 1, 2025, through August 31, 2027. The award funds the implementation and expansion of instrument-based vision screening in primary care pediatric offices across 44 general pediatric practices affiliated with Akron Children's Hospital. The project addresses the challenge that approximately half of...
- Federal Grant Award Summary The National Eye Institute (NEI), under its Vision Research program (CFDA 93.867), awarded a $260,661 Project Grant to The Schepens Eye Research Institute, Inc. for a three-year career development initiative spanning August 1, 2025, through July 31, 2028. The award supports Dr. Levi N. Kanu's mentored research program focused on developing nanomaterial-based growth factor delivery systems to improve therapeutic outcomes for corneal disease. The research plan...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded a K08 Mentored Clinician Scientist Development Award of $236,576 to Dr. Anh Pham at the University of Miami's Bascom Palmer Eye Institute, effective August 1, 2025 through July 31, 2030, under the Vision Research program (CFDA 93.867). This career development grant supports research investigating mitochondrial quality control mechanisms in the ocular outflow facility as a potential contributor to glaucoma development and ocular...
The National Eye Institute (NEI) awarded Ann & Robert H Lurie Children's Hospital of Chicago a Project Grant totaling $200,002 under the Vision Research program (CFDA 93.867) beginning April 1, 2026 and concluding March 31, 2031. This K23 Career Development Award supports Dr. Jennifer Rossen, a pediatric ophthalmologist, in developing an independent surgeon-scientist career focused on improving ocular and non-ocular outcomes for patients with inherited pediatric cataracts. The grant funds intensive mentorship, training, and research activities designed to advance Dr. Rossen's expertise in implementation science, quantitative science methods, prospective clinical trial administration, grantsmanship, and multidisciplinary research collaborations. The primary deliverables of this five-year award include: (1) evaluation of clinicians' current genetic testing practices for pediatric cataracts through focus group studies; (2) creation and maintenance of an artificial intelligence-assisted, web-based open access database documenting genotype-phenotype associations in pediatric cataracts; and (3) assessment of genetic testing efficacy in identifying treatable diseases in pediatric cataract patients. These research activities address the clinical challenge that pediatric cataracts affect approximately 314,000 children annually worldwide and are frequently associated with syndromes containing treatable conditions, yet standardized genetic testing remains low, resulting in missed and delayed diagnoses.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $200.0k | 4/2/26 |