Project Grant K08EY037382
- This $257,785 Project Grant was awarded on April 1, 2025 by the National Eye Institute (NEI) under the Vision Research federal grant program (CFDA 93.867). The grant supports the development of a refillable micromachined lens capsule-based drug delivery device for extended intraocular delivery of biologics and immune-modulating peptides to treat non-infectious uveitis. The key products/services to be delivered under this 4-year grant include: Characterizing and controlling the release of the...
- This Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), provides $247,387 to Stanford University to establish a comprehensive strategy for recruiting, training, and retaining clinician-scientists in ophthalmology research. The overarching objectives are to educate and develop the next generation of clinician-scientists focused on vision-related diseases and disorders, and to enhance research capabilities within ophthalmology...
- This $332,179 Project Grant awarded by the National Eye Institute (CFDA 93.867 Vision Research) supports the development of nanobarrier contact lenses that can provide sustained delivery of the drug cysteamine to treat the ocular complications of cystinosis. The lenses are designed to replace the current 8-times daily eye drop regimen, improving patient compliance and reducing side effects from the preservatives and acidic pH in the eye drops. The project aims to demonstrate the lenses can...
- This $148,568 Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), supports research at Emory University to investigate the role of scleral fibroblasts in refractive development and myopia. The primary objectives are to: 1) Identify characteristics of scleral fibroblasts in mouse eyes that undergo normal refractive development versus those exposed to myopic stimuli, and 2) Determine the role of retinoic acid signaling in driving...
- This Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), supports the development of a novel genetic screening approach termed "Mosaic In Vivo Perturbation (MVP)" to systematically assess gene function in the eye. The $1,387,142 award, effective September 1, 2024 through June 30, 2028, will enable researchers at President and Fellows of Harvard College (Harvard Medical School) to optimize the MVP approach, develop an...
- This $305,321 Project Grant awarded by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) supports the clinical development and commercialization of a topical ophthalmic treatment for neovascular age-related macular degeneration (NAMD). The funding will enable the awardee, Neovascularx, Inc., to advance their AMD101 (rifampicin) compound, which aims to provide a less invasive, home-based alternative to the current standard of care intravitreous injections for...
- The U.S. Department of Defense's Military Medical Research and Development program (CFDA 12.420) awarded a $1,477,500 Project Grant to The Schepens Eye Research Institute, Inc., a non-profit organization affiliated with Harvard Medical School and Massachusetts Eye and Ear. The 3-year grant, awarded on September 1, 2023, will fund research on "Topical Calcitonin Gene-Related Peptide for Corneal Injury Prevention and Regeneration." The Schepens Eye Research Institute, which has...
- This federal Project Grant award of $598,108 from the National Eye Institute (CFDA 93.867 Vision Research) supports the development of innovative ophthalmic imaging technologies and novel objective, quantifiable functional biomarkers for cone photoreceptors. The primary aims are to: 1) Develop next-generation optical coherence tomography (OCT) technologies to enable functional photoreceptor imaging over a wide retinal area and at high topographical resolution; and 2) Develop novel objective,...
- This Project Grant award of $394,285, funded by the National Eye Institute (CFDA 93.867 - Vision Research), supports research at the University of Houston to develop decorin-based drugs for treating corneal scarring and neovascularization. The key objectives are to characterize the binding interfaces of decorin with TGF-β1 and VEGFR2 in order to engineer novel decorin mimetic drugs. This research aims to provide alternative treatment options for preventing corneal opacity and vision loss...
- This federal Project Grant award from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) is supporting research at New York University (NYU) to investigate the mechanism of corneal lens development in the Drosophila model organism. The $142,749 award, spanning September 2025 to August 2027, aims to use genetic, microscopy, and transcriptomic approaches to study the role of the polysaccharide chitin and the central and lattice cells of the fly corneal lens in...
This $260,661 Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) will support a 3-year mentored career development plan for Dr. Levi N. Kanu, an Instructor in Ophthalmology at Harvard Medical School, to foster his transition to research independence in the fields of ocular biomaterials and drug delivery. The award will enable Dr. Kanu to systematically investigate novel techniques for ocular protein delivery, refine his grantsmanship skills, develop leadership and managerial abilities, and foster early career collaborations. The research will be conducted primarily at the Schepens Eye Research Institute, an ophthalmology and vision research non-profit organization affiliated with Harvard Medical School. The project aims to advance scientific understanding and develop innovative treatments for eye diseases and conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $260.7k | 7/26/25 |