Project Grant K23EY037862
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a $733,137 Project Grant to the University of California, Los Angeles on September 15, 2025, with a completion date of March 31, 2030. This award funds research investigating how genetic variation influences disease progression and therapeutic response in age-related macular degeneration (AMD), a leading cause of vision loss in older adults. The project integrates...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded University of California, Irvine $179,964 under the Vision Research program (CFDA 93.867) on March 1, 2025, for a project grant extending through July 10, 2029. The project focuses on developing deep learning-based biomarkers for optic neuropathies using retinal Optical Coherence Tomography (OCT) imaging analysis. The research will employ advanced computational techniques, including deep generative models, neural field image...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded the University of California, Los Angeles a $722,904 Project Grant effective May 1, 2026, through April 30, 2031, under the Vision Research program (CFDA 93.867). The grant supports the ROBUST (Researching OCT Biomarkers in Uveitis Clinical Trials) project, which conducts secondary analysis of optical coherence tomography (OCT) imaging and clinical datasets from four NEI-funded uveitis randomized clinical trials. The project...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $143,031 to the University of California, Berkeley on December 4, 2025, with a completion date of May 31, 2028. This Project Grant funds computational modeling research investigating the role of spatial phase in the selectivity and invariance of neuronal responses in primary visual cortex (V1) and secondary visual cortex (V2) when processing intermediate-level features in...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded a $315,000 Project Grant to the University of Colorado-Denver effective July 1, 2026, through April 30, 2030. The award funds development of a multidisciplinary telemedicine care model designed to address critical gaps in chronic pediatric uveitis management and improve access to specialized care for affected children and families. The project will deliver remote clinical...
- Federal Project Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $255,722 to the University of California, Berkeley, effective September 15, 2025, through August 31, 2027. This Project Grant funds research investigating the role and regulation of a distinct optic nerve microglia population in glaucomatous neuropathy. The research addresses mechanisms of retinal ganglion cell degeneration during ocular hypertension (OHT) by examining...
- Federal Project Grant Award Summary The National Eye Institute (NEI) awarded the University of California, Davis $423,767 under the Vision Research program (CFDA 93.867) for a two-year project period beginning June 1, 2025 and concluding May 31, 2027. The research project investigates the role of myeloid cells as mediators of glaucomatous axon degeneration and evaluates whether nicotinamide adenine dinucleotide (NAD+)-boosting interventions provide neuroprotection through anti-inflammatory...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded University of California, Davis a $719,012 Project Grant effective August 1, 2025, through July 31, 2030, to optimize suprachoroidal adeno-associated virus (AAV) delivery systems for retinal gene therapies in nonhuman primates. The research addresses significant limitations of conventional AAV administration routes by evaluating microcatheterization techniques and...
- Federal Project Grant Award Summary The University of California Irvine received $773,760 in federal funding from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) on September 15, 2025, for a project investigating spatial frequency domain imaging (SFDI) as a diagnostic and therapeutic monitoring tool for thyroid eye disease (TED). Dr. Ediriwickrema's research team will develop non-invasive optical imaging methods to assess tissue properties associated with...
- Federal Grant Award Summary The National Eye Institute (NEI) awarded a $638,625 Project Grant to the University of California, San Diego, effective August 1, 2025 through July 31, 2028, under the Vision Research program (CFDA 93.867). The award funds research to investigate the mechanisms of drusen formation in age-related macular degeneration (AMD), a leading cause of blindness affecting approximately 196 million people globally. The research employs a novel quartz crystal microbalance assay...
The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $287,457 to the University of California, Davis on July 1, 2026, to support a K23 career development project focused on personalized prediction of treatment response and outcomes in patients with non-infectious uveitis (NIU). The project, extending through March 31, 2031, will deliver machine learning (ML) predictive models designed to guide personalized treatment interventions and optimize patient outcomes. Specifically, the award supports two primary deliverables: (1) extraction and analysis of detailed ocular examination data from electronic health records (EHRs) to identify predictive variables, and (2) development and validation of ML-based clinical decision support tools that predict treatment response, disease activity, and complication risk, which can be integrated into real-time clinical workflows to support evidence-based clinician decision-making. The award also funds career development activities for the principal investigator, Dr. Emami-Naeini, including advanced training in bioinformatics, machine learning, and clinical informatics through coursework, health informatics workshops, and multidisciplinary mentorship. These professional development activities are designed to establish Dr. Emami-Naeini as an independent clinician-scientist capable of advancing personalized uveitis care. The project addresses a significant clinical need, as approximately 40% of NIU patients do not respond to first-line immunomodulatory therapies, and the disease carries substantial morbidity and economic burden, particularly affecting working-age populations and underserved rural and socioeconomically disadvantaged communities.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $287.5k | 6/24/26 |