Project Grant K23DK142042
- This federal Project Grant award, in the amount of $531,999.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award is supporting research focused on understanding the role of alternative splicing in the proximal tubules of the kidney and its relationship to the progression of diabetic kidney disease. The research will investigate how diabetes...
- This $166,953 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant was awarded to the Regents of the University of Minnesota, Office of Sponsored Projects Administration, to conduct a pilot, pragmatic, cluster-randomized clinical trial to evaluate the feasibility of an intervention to increase the use of SGLT2 inhibitor medications after...
- This $192,215 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) will support a research project titled "Assessing Patient-Centric Factors and Enhancing Risk Communication to Improve Treatment Persistence in Kidney and Cardiovascular Care" at the University of California, San Francisco (UCSF). The project aims to develop an effective risk communication aid to...
- This $128,286 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research into the mechanisms of renal lipotoxicity and its contribution to the development of chronic kidney disease (CKD). The principal investigator will investigate the protective role of the FAF2 gene knockout in mitigating palmitate-induced lipotoxicity in...
- This federal Project Grant award, valued at $209,832.00 and provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research, will support research at New York University (NYU) to improve the understanding of the role of the autonomic nervous system (ANS) in the cardiovascular complications of chronic kidney disease (CKD). The 5-year project aims to develop the candidate's skills in ANS...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through the Diabetes, Digestive, and Kidney Diseases Extramural Research Program (CFDA 93.847), awarded a $671,986 Project Grant to Rutgers, The State University of New Jersey, to conduct research aimed at strengthening the evidence-base for medication prescribing in older adults with chronic kidney disease (CKD). The key objectives of the 4-year project are to: 1) evaluate the effectiveness of renoprotective therapies...
- This $131,085 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports a 5-year research project led by Dr. Arianne Caudal at The Leland Stanford Junior University to elucidate the cardiac-protective mechanisms of SGLT2 inhibitors. The project aims to leverage human induced pluripotent stem cell-derived cardiovascular cells, single-cell RNA sequencing, metabolomics, and large-scale drug-protein interaction determination to...
- This Cooperative Agreement award of $2,367,892 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund research to develop and evaluate a novel approach to mitigate the risk of diabetic ketoacidosis (DKA) in people with type 1 diabetes (T1D) and chronic kidney disease (CKD) who are taking sodium-glucose cotransporter (SGLT) inhibitor medications. The project aims...
- This $380,466 Cooperative Agreement, awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a study titled "CARDIOVASCULAR AND RENAL PROTECTION WITH SGLT2 INHIBITION IN KIDNEY TRANSPLANT RECIPIENTS (RENAISSANCE)". The project aims to examine the potential benefits and risks of using sodium-glucose cotransporter-2 (SGLT2) inhibitor drugs in kidney...
- This Project Grant award of $830,500.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) supports research investigating the role of glycosphingolipids in kidney disease associated with diabetes and obesity. The key objectives are to: Test whether inhibiting glucosylceramide synthesis in podocytes, renal tubules, or the immune system can prevent progression of kidney disease in mouse...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will provide $193,809 to Yale University to assess the efficacy of sodium-glucose cotransporter-2 (SGLT2) inhibitors for the treatment of acute cardiorenal syndrome. The candidate, an Instructor of Medicine (Nephrology) with 3 years of training in acute kidney injury and clinical trials, will receive mentorship from experts in heart failure, renal physiology, and biostatistics to become an independent clinical researcher in cardiorenal syndromes. The proposed study aims to evaluate the ability of SGLT2 inhibitors, a class of oral anti-hyperglycemic drugs, to improve outcomes in patients hospitalized with acute heart failure who develop acute kidney injury, a common and serious complication. The award will fund the candidate's research activities from August 1, 2025, to April 30, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $193.8k | 8/1/25 |