Project Grant K23DK138238

Award Date 8/15/24
Completion Date 5/31/29
Dollars Obligated $568K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Aurora, CO 80045, USA
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This $183,600 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research conducted by the University of Utah to investigate the impact of dietary changes on the gut microbiome and its relationship to eosinophilic esophagitis (EoE). The 5-year research project aims to: 1) characterize the fecal microbial composition, gene expression, and metabolites associated with...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $1,485,507 to The Children's Hospital of Philadelphia (CHOP) to conduct research on the role of CD73 in esophageal epithelial homeostasis. The 4-year project aims to: 1) define the requirement of squamous epithelial CD73 in esophageal homeostasis and response to eosinophilic esophagitis...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to elucidate the mechanisms by which the aryl hydrocarbon receptor (AhR) mediates both protective and detrimental effects on eosinophilic esophagitis (EoE), an allergic disease of the esophagus. The $1,246,628 award, effective from August 15, 2024 through June 30, 2029, will support the...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $1,222,594 to Vanderbilt University Medical Center to investigate the role of glutathione peroxidase 3 (GPX3) in regulating esophageal epithelial remodeling, subepithelial fibrosis, and eosinophil recruitment associated with eosinophilic esophagitis. The research aims to determine...
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This Cooperative Agreement award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a $389,578 multi-center clinical research project focused on improving the treatment of achalasia, a rare esophageal motility disorder. The project, titled "Precision Medicine in Achalasia - PREMEDIA", aims to test an innovative, tailored approach to per-oral endoscopic...
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