Project Grant K23AR084603

Award Date 7/1/24
Completion Date 6/30/29
Dollars Obligated $175K
Federal Grant Program
93.846
Assistance Type
Project Grant
Place of Performance
Boston, MA 02114, USA
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The key products and services to be delivered through this grant include: 1) Examining the association between knee imaging biomarkers (MRI, CT) and different pain phenotypes (nociceptive, neuropathic-like, nociplastic) in KOA patients; 2) Investigating the relation between pain phenotypes and imaging biomarkers to persistent pain 6 months post-knee replacement; and 3) Identifying the relationship between co-existing knee imaging biomarkers and pain phenotypes. This research aims to advance the understanding of the discordance between structural damage and pain in KOA, which could lead to improved clinical trial designs and the identification of more effective treatments for the millions of Americans living with this condition.

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